78 results
Collection of skin tissue and blood samples from patients with mild to moderate psoriasis for efficacy testing of a reference compound, for subsequent testing of a new therapeutic in a humanized mouse model.
The aim of the project is to study the effect of "UCB1577571 en CA050_01953" on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
The main objective of this study is to investigate the effect of a topically applied emollient enriched with barrier lipids on the barrier properties of skin of AE patients.
Are Alphabodies against IL23 effecive in the transplant model of psoriasis
The specific aim of the project is to determine the efficacy of Spherical Nucleic Acids (SNAs) on psoriasis skin biopsy gene expression in vitro.
The aim of the project is to study the effect of GRTs on the synthesis and cytokine release in psoriasis lesions. Thisinformation can establish the right formulation and dose of GRTs for further research.
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
Primary objective* To characterize and monitor wound healing after a standardized, induced skin trauma Secondary objectives* To evaluate safety and tolerability of biopsy-induced skin trauma
With this pilot feasibility study, the feasibility of and satisfaction with an eHealth and serious gaming training based on psychological expectancy mechanisms are evaluated.
The aim of the project is to study the effect of SNA on the gene expression in psoriasis lesions. This information can establish the right formulation and dose of SNA for further research.
The aim of the project is to study the effect of chromene derivatives on gene expression in psoriasis lesions. This information can establish the right dose of chromene derivatives for further research.
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
The aim of the project is to study the effect of GRT on the synthesis and cytokine release in psoriasis lesions. This information can establish the right formulation and dose of GRT for further research.
The aim of the project is to study the effect of COM test compounds on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
Collect data to determine whether early pimple markers can be identified using images and a skin expert review or algorithm for at least 1 day before they are visible (visible or tangible) for the subject (self-detection).
1) Does FSAP activation in plasma of HAE patients contributes to bradykinin formation? 2) Study the inhibitory efficacy of c1-inhibitor towards kallikrein and FSAP towards bradykinin formation in a endothelial cell-based system. 3) test the efficacy…
The aim of the project is to test BS6.890C in the prophylactic transplant model of psoriasis.
ln this study effect of 3 novel compounds on the development of psoriasis in the humanized mouse model isinvestigated. The efficacy is compared to one registered drug, namely Remicade(R).
Characterization and extending the use of the humanized mouse model for psoriasis for pre-clinical testing of new drug.Limited screening of compound B for a pharmaceutical company.Therefore, depending on the success rate of transplantation and…
In previous projects a number of compounds were tested that had a positive effect in the transplant model of psoriasis. However, it proved difficult to prepare formulations that were stable enough to use in clinical studies. A new compound (CD07813…