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Ki-67 and cytokeratin 16 expression in several lesion types of hidradenitis suppurativa compared to keratosis pilaris and psoriasis inversa. A pilot investigation

To investigate whether the upregulation of CK16 and Ki-67 (a marker for cell proliferation) in the FPSU is specific for HS, measured in inflammatory nodules and pseudo-comedones, in comparison to other dermatologic conditions that have comparable (…

Expression of cytokeratins and notch in the healthy folliculopilosebaceous unit

1) to examine the expression of cytokeratins and Notch in healthy human FPSUs at different segments. 2) to describe the association between expression of the cytokeratins and Notch 1 in the FPSUs of healthy volunteers.

THE MORPHOLOGY OF THE BASEMENT MEMBRANE ZONE OF HAIR FOLLICLES IN HIDRADENITIS SUPPURATIVA: A PILOT STUDY

To describe the composition of the BMZ along the interfollicular and follicular epidermis of perilesional HS skin and to investigate whether the expression of these proteins differs from normal skin of healthy control patients. Additionally, a…

Genetics of hidradenitis suppurativa

To determine which gen defects are associated with hidradenitis suppurativa.

Exome Sequencing and Molecular Profiling in Patients with Hidradenitis Suppurativa (HS)

To Identify genetic variants and clinical phenotypes associated with risk of HS and to characterize the key cellular and molecular mechanisms and pathways involved in the pathogenesis of moderate-to-severe HS.