20 results
Assess feasibility of development of skin colour independent assessment of skin AGE accumulation by measurement of skin autofluorescence in persons with dark skin
To assess the efficacy and patient safety of (1)fractional laser treatment in combination with NB- UVB,(2) fractional laser treatment in combination with NB- UVB and topical corticosteroids versus NB-UVB treatment alone.
Primary: to compare the efficacy and safety of different punchdepths and punchsizes in punch grafting in patients with segmental and non-segmental vitiligo. Secondary: to assess the practical aspects and patients preference of different punch…
The purpose of the present randomized controlled pilot study is to assess the efficacy, safety and practical aspects of autologous epidermal cell suspension grafting using ReCell in segmental vitiligo and piebaldism patients. Results of this study…
The objective of this study is to evaluate the difference in clinical effects (onset and degree of repigmentation) of NB-UVB and fluticasone proprionate vs NB-UVB alone.
The primary objective of this study is to assess the efficacy and safety of non ablative and ablative fractional lasers in various pigment disorders.
Proof that laser treatment will be better than the routine method using curettage. Besides it is claimed that laser treatment is less painfull.This will be assessed by photography, in which only black white (grey) evaluations are made. Colours are…
Our purpose is to establish whether the frequently observed absence of tumor regression in the presence of infiltrating T lymphocytes is due to a lack of T cell effector function or due to an inhibitory influence of the tumor microenvironment on T…
The primary objective of this study is to compare the effectiveness of two different phototherapy protocols (continuous treatment for 6 months, or 2 continuous treatments for 2 months separated by one month interruption (2-1-2-1), with a total…
The primary objective of this study is to assess the efficacyand safety of the fraxel laser as compared to a potent bleaching cream (triple therapy) in the treatment of melasma.
The objective of this study is to evaluate the clinical effects (start and grade of repigmentation) of NB-UVB versus 308-nm Excimer lasertherapy on pigment spread after minigrafting in vitiligo patients.
Primary: to assess the efficacy and safety of autologous epidermal cell suspension grafting using the ReCell kit after CO2 laser abrasion with superficial full surface ablation, fractional laser treatment and conventional (deep) full surface CO2…
In this study, we will conduct a randomized controlled pilot study to assess the effectiveness of the EQoL-intervention combined with standard of care versus standard of care alone.
1. To investigate the relative contributions of different ocular abnormalities to the visual function.2. To investigate the precise relationship between ocular pigmentation and the development of the visual system abnormalities.
* To assess the incidence of PIH in previous studies using the heat pain assessment* To assess the characteristics of PIH in these subjects (Melanin Index, skin colour, morphology)* To evaluate the severity of the PIH in these subjects
Primary: to assess the efficacy and safety of RenovaCell grafting combined with 311 nm UVB therapy and topical anti-inflammatory therapy for the treatment of stable non-segmental vitiligo. Secondary: to assess, satisfaction, cosmetic acceptability,…
- Assess whether early markers (in blood and/or skin) can predict the clinical response to treatment (i.e. surface area of repigmented skin after 3 and 6 months of standard of care treatment).- Assess the relation between markers in blood, skin…
The purpose of this study is to investigate how quickly and to what extent PF-06651600 is absorbed and eliminated from the body (this is called pharmacokinetics). In this study doses of PF-06651600 labeled with very low doses radioactive (14C) will…
The primary objective is to compare the efficacy, as measured by recurrence-free survival (RFS) by blinded independent central review (BICR), of bempegaldesleukin plus nivolumab versus nivolumab in patients with completely resected Stage IIIA (lymph…
To determine which biological processes play an essential role in immune-pathological changes in vitiligo skin depigmentation.