25 results
Primary ObjectiveThe primary objective for this study is to compare the clinical efficacy of weekly abatacept in combination with methotrexate to methotrexate alone in achieving Remission, defined as SDAI less than or equal to 3, at Week 24.…
This trial will provide definitive answers with regard to the anti-inflammatory effects of Vitamin D in Crohn*s disease.
To investigate whether statin treatment can prevent or delay the development of RA in persons at increased risk of RA.
To improve physical activity levels and physical activity patterns in children with JIA by means of cognitive behavioural training based on the social cognitive theory and the health promotion model, delivered by internet and supported by group…
Primary objective: The primary objective of the study is to determine the effect of concentration/meditation on the innate immune response induced by a lipopolysaccharide (LPS) challenge. Secondary Objective(s): There are two secondary objectives:1…
Confirm an association between RA and periodontitis and unravel pathogenic mechanisms underlying this association.
The primary objective of the study is to assess the safety and immunogenicity of V212 in a population of adults with autoimmune disease.
The primary goal of the current study is to study the safety of and serological response to the MMR booster vaccination in JIA patients. Based on a retrospective analysis we hypothesize that MMR vaccination does not aggravate JIA disease and that…
The aim of the proposed pilot study is to explore the efficacy of rTMS in inducing a (transient) localized increase in brain activity of MS patients which is hypothesized to be beneficial for cognitive functioning. This is the first step that needs…
to identify high risk groups in need for more specific and appropriate guidance. Also to provide adequate counselling and help.
To assess the effect of adalimumab and rituximab on the safety and efficacy of vaccination with T cell-dependent and T cell-independent primary and recall antigens.
To establish efficacy of pre-travel vaccinations by determination of protective serum antibody titres against hepatitis A, DTP and polysaccharide Vi of Salmonella typhi. To quantify health risks related to preventive actions and consequences of…
In this research the effects of Type D and mindfulness on psychological well-being and physical functioning is reported in two different treatment groups. Rheumatoid arthritis is a chronic disease. Personality could be an important factor in…
To determine whether a second, booster, influenza vaccination leads to a higher seroprotection rate in SLE patients, as compared to a single vaccination.
The objective of the study is to evaluate a fall prevention program for persons with RA. The primary parameter is to reduce fall incidence in the participants of the fall prevention program.
To improve physical activity levels and physical activity patterns in children with JIA by means of cognitive behavioural training based on the social cognitive theory and the health promotion model, delivered by internet and supported by group…
The primary goal of this study is to evaluate the efficacy and safety of influenza, pneumococcal and hepatitis B vaccination in patients with rheumatic autoimmune diseases treated with immunosuppressive therapy compared to healthy controls. The…
In this pilot study patients treated with a single course of rituximab or treated with multiple courses of rituximab, matched RA controls treated with methotrexate and healthy controls will be included in order to answer the following questions:1.…
The main aim of this implementation research is to systematically screen all RA patients of Reade rheumatology and revalidation centre in Amsterdam for their cardiovascular risk profile and if necessary to treat them for cardiovascular risk factors…
The aim of the study is to evaluate the efficacy of sensor augmented pump (SAP) therapy with MiniMed* 640G and SmartGuard* in preventing hypoglycemic events in comparison with continuous subcutaneous insulin infusion (CSII) therapy in type 1…