94 results
To examine the effect of BCG vaccination on the composition and function of the bone marrow.
To evaluate whether neuromuscular ultrasound discriminates between patients with and without ICU-AW.To detect differences between patients that do and do not have ICU-AW in order to determine relevant cut-offs which can be used in future diagnostic…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.
To describe the wound related complication rate in post-bariatric body contouring surgery patients who are treated according to a new guideline and assess the factors associated with a higher complication rate.
This research project aims to determine the feasibility of setting up a randomized controlled trial to study the effects of different fluid management protocols on the outcome of mechanically ventilated pediatric patients with acute infectious lung…
To characterize the interaction between the gut microbiome, related metabolites, immune function, and perceived complaints in QFS-patients, CFS-patients, and healthy individuals.
The primary objective of this study is to monitor changes in oral health during a 3.5-month naval mission and once one month thereafter.
The primary objective of the study is to assess the function and effect of deiodinase type 3 in PMN*s and the mechanisms behind its induction following activation of these cells.
A previous study of from our laboratory showed that administration of the drug C1-INH (100E/kg) significantly reduced the concentration of circulating pro-inflammatory cytokines, such as IL-6, in healthy male volunteers during human experimental…
Predicting fluid responsiveness during PLR and fluid challenge (FC) by changes in (Pms).
To examine the effect of BCG as an adjuvant on DTP vaccination, and to investigate the non-specific training effects of BCG and DTP, alone and in combination, on the innate immune system.
1) To determine whether vaccination with yellow fever results in a higher cytokine response upon restimulation in vitro with non-related infectious pathogens, compared to the response before the vaccination.2) To determine whether BCG vaccination…
The aim of this study is to explore the prevalence of HAND in people living with HIV.
To develop a screening test to predict ICU-AW at an early stage in patients admitted to the ICU. Also by prospectively following the patient group in time, this study aims to describe the natural history and functional limitations in patients…
The aim of this study is to create a prognostic model enabling the clinician to predict the outcome of a septic episode. Furthermore, by getting more insight in the pathophysiologic proces of sepsis, we could discover new possible targets for future…
The aim of the study is to explore the prevalence of HAND in people living with hiv.
to investigate if small nerve fibres are affected in patients with ICU-AW
Primary Objective•To assess the pharmacodynamic response after single dose administration of NOX H94 in healthy subjects during experimental endotoxemia.Secondary Objective• To determine the pharmacodynamic effects of NOX H94 after single dose…
1. Creating a reproducible and valid method for adenosine measurement2. Studying the effect of dipyridamole on the endogenous adenosine concentration before and after CPT.
In this study we aim to develop a predictive model for septic ICU*patients enabling the clinician to make a customized risk stratification and asses the patient*s immune status.