56 results
Clarifying the qualitative and quantitative aspects of the T cell response targeting and controlling polyomavirus BKV.
the primary objective is to investigate if HIV-infected patients treated with a NNRTI display higher peripheral T cell apoptosis than those treated with a PI. Secondary objectives are to investigate 1) which apoptosis pathway is involved in…
To assess the prevalence of (recent) hiv infections, hepatitis B and C, and (related) risk behaviour among detainees in PI the Geerhorst, Southern Limburg in the Netherlands.
To gain insight into the prevalence of HBV and HCV and risk factors for HBV and HCV among (former) tatooists and piercers and individuals with multiple tattoos or piercings.
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What is the attack rate of symptomatic and asymptomatic (tropical) diseases in long-term travelers.Which behavioral risk factors are of influence on the attack rates? (compliance with preventive measures, other risk behaviour)Are certain groups of…
1. To gain insight into the prevalence and incidence of HIV and other sexually transmitted infections and blood borne infections among visitors of the STI clinic in Amsterdam.2. To gain insight into risk factors and risk behaviour among visitors of…
The primary objective of this Registry is:• To assess the durability of sustained virologic response (SVR) following treatment in a Gilead-sponsored hepatitis C study.The secondary objectives of this Registry are:• To determine whether subsequent…
The main objective of this study is to investigate the effectiveness of the self-help program compared to a waiting-list control group in reducing depressive symptoms. Secondary objectives include the investigation of moderators and mediators of…
1. To examine whether epigenetic inhibitors can reverse exhaustion of HIV-specific CD8+ T cells.2. To determine whether HIV-specific CD8+ T cells have altered expression of post-transcriptional regulators.
Primary Objective: To assess the effect of early extra measles immunization on the humoral immunity against measles 6 years after MMR-1 at 14 months of ageSecondary Objective(s): •Determine the effect of early extra measles immunization on the…
Objective: To investigate the adipose tissue response upon ex vivo SARS-CoV-2 infection, more specifically to answer the following questions:1. Is adipose tissue permissive to direct SARS-CoV-2 infection? 2. Are adipose tissue-derived factors…
To determine the burden of disease due to RSV in older adults.
To study phenotypic and functional characteristics of hepatic lymphocytes in patients with viral hepatitis or other liver related diseases.
• Bestaan er serologische testen die geschikt zijn om doorgemaakt infecties met Sars-Cov2 aan te tonen?• Hoe wijd verspreid is Sars-Cov2 onder het zorgpersoneel en hoe verhoudt zich dat tot de Nederlandse bevolking?• Hoe ontwikkelt zich het…
The primary objective of this study is to determine the difference in the health-related quality of life (determined by SF-36) between patients with and without an established SARS-CoV-2 infection in a 12 month follow-up period in patients managed…
To determine the burden of disease due to RSV in young term born infants.The active cohort study is expanded to other family members during the COVID-19 pandemic to gain insight in COVID-19 related burden to families. In addition we would like to…
To characterize the immune response and gene expression profiles in blood of chronic HBV patients who present with a flare after treatment with antiviral therapy in order to be able to predict spontaneous resolution of flares in the future.
To assess achieved immunity against COVID-19 across the different age groups in The Netherlands by testing a representative part of the Dutch population for the presence of SARS-Cov-2 specific antibodies in serum
Objective: To evaluate the humoral response and estimate the prevalence of antibodies against SARS-CoV2 in children during the COVID-19 outbreak in the Netherlands.