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A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid as compared to standard of care (SOC) treatment

To evaluate the safety and clinical benefit of NexoBrid in hospitalized children (0-18 years) with deep partial and/or full thickness thermal burns of 1-30% TBSA and to compare NexoBrid to standard of care (SOC).

Pilot study to determine the utility of a Likert-type scale to assess patients* experience of radiation dermatitis during radiotherapy for breast cancer.

Objective: determine whether a Likert-type scale scoring system, specified for skin irritation reactions (erythema, itching, burning sensation of skin and general irritation of skin) can function as a tool to score the radiation-induced dermatitis…

Child Abuse Inventory at Emergency Rooms (CHAIN-ER); Detection of Child Abuse at Emergency Rooms in Utrecht (the Netherlands): effective?

1. to provide data in children presenting with physical injury at EDs on the predictive value of Sputovamo2. to address the added predictive value of early phase inquiry with other health care providers in establishing a diagnosis of child abuse

Distribution and time course of serum procalcitonin levels in burn patients.

This study aims to design a nomogram for the course of serum pro-calcitonin in burn patients. For this purpose, a new, sensitive assay will be used. It is expected that the nomogram will help to differentiate between patients with a systemic…

The development and examination of an intervention aimed at youths who have to be treated at the emergency department of a hospital as a result of excessive alcohol use.

Aim of the study is to develop and test a brief intervention for adolescents who have to be treated in the emergency department of a hospital due to excessive alcohol use.

Pressure and Silicone treatment in Hypertrophic Scarring

The objective of our observational clinical trial is to quantify the apoptosisrates of fibroblasts and growth-factorchanges in hypertrophic (burn) scars treated with pressure and/or silicone therapy.

Validation of revised diagnostic criteria for Complex Regional Pain Syndrome.

The primary aim of the proposed multi-site study will be to determine internal and external validity of the proposed new diagnostic criteria.

The First Bratelle study, a prospective, single-arm, pilot study to confirm the efficacy of the Bratelle breast-pads, that has been experienced by a small group of individual patients, in a larger group and in a controlled setting.

Primary, improvement of the quality of life.Secondary, reduction of pain and a decrease of the number of treatments by a breast oedema therapist.