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A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid as compared to standard of care (SOC) treatment

To evaluate the safety and clinical benefit of NexoBrid in hospitalized children (0-18 years) with deep partial and/or full thickness thermal burns of 1-30% TBSA and to compare NexoBrid to standard of care (SOC).

The development and examination of an intervention aimed at youths who have to be treated at the emergency department of a hospital as a result of excessive alcohol use.

Aim of the study is to develop and test a brief intervention for adolescents who have to be treated in the emergency department of a hospital due to excessive alcohol use.

Pressure and Silicone treatment in Hypertrophic Scarring

The objective of our observational clinical trial is to quantify the apoptosisrates of fibroblasts and growth-factorchanges in hypertrophic (burn) scars treated with pressure and/or silicone therapy.

The First Bratelle study, a prospective, single-arm, pilot study to confirm the efficacy of the Bratelle breast-pads, that has been experienced by a small group of individual patients, in a larger group and in a controlled setting.

Primary, improvement of the quality of life.Secondary, reduction of pain and a decrease of the number of treatments by a breast oedema therapist.