54 results
To validate and assess the impact of the use of the MyCyFAPP system for self-management in children with CF, more specifically the effect on patients* quality of life, nutritional status, gastro-intestinal symptoms, general wellbeing and economic…
The first objective is to improve preoperative staging with 3T NANO-MRI regarding the detection of lymph node metastases in patients with a pancreatic or periampullary carcinoma when compared to a conventional contrast-enhanced CT or MRI. Other…
The objective of the study is to investigate whether early ERC plus ES in patients with suspected APB and a predicted severe disease course without cholangitis, lowers the incidence of a composite endpoint of mortality and severe morbidity. Major…
Determine whether micellar curcumin (Espera®) is able to improve the Systemic Immune Inflammation index in operable PDAC patients OR (metastasized) pancreatic cancer patients with stable disease after standard of care treatment.
The aim of this research is to investigate whether it is feasible and safe to treat operated pancreatic cancer patients who have completed standard of care treatment with dendritic cell immunotherapy using dendritic cells loaded with autologous…
Primary objectiveTo investigate whether the addition of preoperative radiochemotherapy to the standard treatment, consisting of explorative laparotomy, pancraticoduodenectomy if possible, followed by adjuvant chemotherapy, improves the overall…
It is a two-step approach study: The main objective in the first approach is to obtain a mathematical predictive model (MPM) adapted to each patient*s gastrointestinal conditions that calculates the optimal amount of enzymatic supplements for the…
Determine the efficacy and safety (using objective response rate) of tremelimumab in patients with advanced solid tumors (UBC, PDAC, TNBC).
The objective of this study is to prospectively document the performance of a fully covered self expanding metal stents (FCSEMS) for treatment of pancreatic duct strictures in patients with painful chronic pancreatitis.
To determine whether micellar curcumin is able to restore functional lymphocytes in pancreatic cancer patients with stable disease after standard of care treatment.
The first part of the study will focus on the feasibility of dendritic cell immunotherapy for pancereatic cancer patients.If this treatment is deemed feasible we will investigate immune-response, immune profile, clinical activity and safety and…
This study has been transitioned to CTIS with ID 2024-517267-23-00 check the CTIS register for the current data. The aim of this research is to investigate whether it is feasible and safe to pre-operatively treat patients who will undergo a distal…
The aim of this research is to investigate whether it is feasible and safe to treat operated pancreatic cancer patients who have completed standard of care treatment with dendritic cell immunotherapy using dendritic cells loaded with autologous…
Primary aim of this study is to validate easy and reliable tests to detect EPI in patients after gastrointestinal surgery. The 72-hour faecal fat quantification (gold standard), will be compared with a shortened version of 24-hours, the FET and 13C-…
Main objective: to assess the effects of PEG treatment on bile acid homeostasis in cystic fibrosis patients. Secondary objective: to assess the effects of PEG treatment on gastrointestinal symptoms and quality of life, and on gut health-related…
Primary: To evaluate the ability to culture PDEC organoids from pancreatic duct biopsies. Secondary: (i) To evaluate ion transport in PDEC organoids derived from pancreatitis patients. (ii) To evaluate the ability of duodenal organoids to mimic ion…
To assess the safety of a novel care pathway in which patients, with a predicted mild course of acute pancreatitis, are discharged early with remote home monitoring.
To investigate the feasibility of using 18F-PSMA PET-CT as a tumor-specific molecular imaging in PC, thus allowing for improved detection, therapy selection, and therapy response assessment.
Investigate whether the use of the Hot AXIOS lumen apposing metal stent is superior to standard plastic pigtails stents for drainage of infected pancreatic necrosis.
To investigate safety and tolerability as well as the induced immune response upon MesoPher/mitazalimab combination therapy in metastasized pancreatic disease after (modified) FOLFIRINOX.