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Intraoperative assessment of microcirculation with Laparoscopic Laser Speckle Analysis (lapLASCA) in patients elected for colorectal surgery for prediction of anastomotic leakage in colorectal anastomoses.

Experimentally, develop a software algorithm to objectively assess the microcirculation quality of the colorectal wall, intraoperative, by laparoscopy to predict the probability of developing anastomotic leakage, with the intention to develop a…

Seroprevalence of hepatitis E virus infections among vegetarians.

In the present study we aim to test the hypothesis that the reservoir of HEV in the Netherlands are animals that are bred for meat consumption. Therefore we want to compare the HEV seroprevalence in vegetarians and in people with a very low meat/…

Ammonia detection in Helicobacter pylori infections with the Ammonia Breath Analyzer (ABA) demonstrator. A pilot study to investigate the clinical application of the ABA.

The aim of this study is to assess the change of ammonia exhaled in Helicobacter pylori (HP) positive patients compared with patients that are not HP infected after urea administration. In principle, in this pilot study, the results of Kearney et al…

MR imaging of acute appendicitis in adults

Primary Objective: To determine the sensitivity and specificity of MRI in a consecutive series of adult patients suspected for acute appendicitisSecondary Objective(s): Is MRI of additional value in adult patients with inconclusive US? And is…

Prevalence of Tropheryma whipplei in duodenum and colon, using real-time PCR

To determine the prevalence of T. whipplei in duodenum and colon in a random population of patients whom will undergo an endoscopy at the VUmc

MR Imaging of acute appendicitis in children

To determine the value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis

Study of susceptibility to bacterial gastroenteritis

In case of food- or water related outbreaks of bacterial gastroenteritis, the regular research of Municipal Health Services (GGD) and the Food and Consumer Product Safety Authority (VWA) aims at control of the outbreak.The aim of this project is to…

Post travel screening
Screening for relevant parasitic infections in asymptomatic travellers returning from the tropics

To determine the usefulness of multiplex real-time pcr to detect asymptomatic parasitic infections in travellers returning from the tropics.

*The use of fecal calprotectin in detecting immunotherapy induced colitis and feasibility for the use of immunohistochemical markers in patients receiving checkpoint inhibitors*- a pilot study

Primary: To determine fecal calprotectin in patients treated with checkpoint inhibitors. Secondary: To describe endoscopic and histologic findings in patients with symptoms that may indicate colitis.To study cytokine production profiles of the…

Helicobacter Pylori determination in a Fecal Immunochemical Test (FIT) - a proof of concept -

To evaluate the accuracy of H. pylori determination in FIT