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Effect of donor human milk on severe infections and mortality in VLBW infants, a double blind randomized controlled trial

To determine whether (supplemental) human donor milk has beneficial effects (in terms of reduction of infectious episodes and mortality) when compared to (supplemental) preterm formula during the first 10 days of life in VLBW infants. Amendement ESS…

Antibiotic treatment alone for children with acute appendicitis; a prospective cohort study part of the Antibiotic versus Primary Appendectomy for Children with acute appendicitis; the APAC trial.

1. What is the complication rate of the initial antibiotic treatment strategy for acute simple appendicitis (radiological proven) in children aged 7-17 years old?

A randomized, placebo-controlled, double blind volunteer study into the effect of milk ingredients on gastroenteritis caused by an attenuated E. coli.

We want to determine whether Lacprodan® PL-20 can effectively protect against enterotoxigenic E.coli induced travellers* diarrhea in humans. In the present double-blind, placebo-controlled, randomized parallel study, the effect of oral milk protein…

Ammonia detection in Helicobacter pylori infections with the Ammonia Breath Analyzer (ABA) demonstrator. A pilot study to investigate the clinical application of the ABA.

The aim of this study is to assess the change of ammonia exhaled in Helicobacter pylori (HP) positive patients compared with patients that are not HP infected after urea administration. In principle, in this pilot study, the results of Kearney et al…

A randomized, placebo-controlled, double blind human trial into the effect of Protecflor on gastroenteritis caused by attenuated E. Coli

We want to study whether consumption of Protecflor can improve the resistance of humans to intestinal ETEC infection. An important parameter of intestinal resistance is the so-called colonization resistance. The colonization resistance is inversely…

The influence of a host genetic risk factor on H. pylori induced immune cell activation

To assess the involvement of a specific genetic risk allele on oxidative stress induced by neutrophils in relation to H. pylori infection.