145 results
To investigate what CTC iodine tagging-only bowel preparation gives a high image quality and readability of the CTC together with a high patient acceptance.
To validate FDG-PET segmentation tools for radiation target volume definition by correlation of CT and FDG-PET volume measurements with histology of nodal metastases of squamous cell carcinoma of the head and neck.
The aim of this study is to determine whether chromoendoscopy, including polypectomy of all detected lesions, reduces the development of colorectal neoplasia in Lynch syndrome patients at follow-up endoscopy.
To determine if there is an increase of skin-autofluorescense in subjects undergoing elective colorectal surgery.
(1) To evaluate the feasibility and accuracy of confocal endomicroscopy during colonoscopic surveillance; (2) To compare the accuracy of CE / NBI / AFI with the accuracy of confocal endomicroscopy for the endoscopic differentiation of adenomatous…
1) To identify a tumour genetic profile that is associated with early metastatic spread in patients presenting with oesophageal cancer and no evidence of distant metastasis at the time of diagnosis.2) To distinguish oesophageal cancer patients who…
The aims of this study are: 1) to evaluate the neoplasia miss-rate of AFI in patients with longstanding UC during colonoscopic surveillance; 2) to evaluate the feasibility of miniprobe-based confocal endomicroscopy in these patients; 3) to compare…
To compare the yield of autofluorescence guided targeted biopsy versus four-quadrant random biopsy in the evaluation of patients with known occult neoplastic lesions in Barrett*s Esophagus.
The aims of the study are: 1) to characterize the mucosal morphology and vascular pattern of neoplastic and non neoplastic mucosa by NBI and standard White Light Endoscopy (WLE) in the upper gastrointestinal tract; 2) to compare the accuracy of NBI…
To evaluate the effectiveness of optimization of CEA measurements after curative resection of stage II, III and IV colorectal carcinoma. The short-term effectiveness will be quantified in percentage of patients that are eligible for curative…
To determine the additional value of NBI-ME to conventional endoscopy in the surveillance of patients with intestinal metaplasia and dysplasia, i.e. to evaluate whether the use of NBI-ME is superior to conventional endoscopy in the detection of…
To determine the feasiblity of the detection of disseminated tumor cells in bone marrow with RT-qPCR
To recognize the distribution pattern of 111In-bevacizumab in patients who do not show response on treatment with bevacizumab. The ultimate goal is to identify and select patients who can be successfully treated.
The aims of this study are to assess the additional value of NBI in comparison to white-light endoscopy (WLE) for the detection and classification of HPs, SAs, MPs and adenomas in patients with HPS.
1) to compare NBI and standard White Light Endoscopy (WLE) for the detection of neoplasia during colonoscopic surveillance of patients with longstanding UC2) To determine the accuracy of Kudo*s classification in distinguishing neoplastic from non…
The primary objective of this study is to determine the sensitivity of the marker bevacizumab-IRDye800CW using innovative NIR fluorescence endoscopy (visualizing with wide-field endoscopy, measuring with MDSFR/SFF spectroscopy and optionally…
Primary objectiveThe primary objective of this trial is to determine the visibility and positional accuracy of laser marks applied by the NvisionVLE Imaging System.
Primary objective: - To determine the feasibility of molecular fluorescence endoscopy using the fluorescent tracer EMI-137 in order to identify dysplasia and/or malignant lesions in patients with Barrett*s esophagus. - To evaluate the safety of EMI-…
Primary objective (part 1)* Establish the feasibility of MR-based target delineation for radiotherapy treatment planning for gastric cancer. Secondary objectives (part 2)* Assess the volumetric differences between clinical target volumes before and…
Evaluation of the feasibility of the combination of (DW-)MRI and digital FDG-PET/CT for prediction of response to chemoradiation therapy.