48 results
The primary objective is to set-up a well-defined sandwich ELISA method to measure the levels of Ara h6 in blood after peanut consumption.
To assess the correlation between the presence of GIP in urine/ faeces and symptoms after a single dose gluten provocation (mimicking the daily risk of gluten ingestion) in patients with coeliac disease adhering to a strict gluten-free diet.
To assess whether changes in insulin sensitivity through dietary interventions affect postprandial bile acid metabolism and kinetics. Secondary objective: to assess TGR5 and FXR mediated pathways in insulin resistant and insulin sensitive states.
The primary objective of CDfuture is to provide duodenal biopsies of patients with and without CD, and venous blood samples, to continue CD research as described above.
The aim of our project is to perform a novel mass screening to detect CD in 12 months-4 years old children who visit the YHCCs in a well-described region in the Netherlands, to show that it is feasible, efficient, cost-effective and well accepted by…
The purpose of this study is to determine how diagnostic delay of CD affects the burden of CD to patients and society in terms of healthcare and mental healthcare utilisation and socioeconomic costs.
Evaluation of a multidisciplinary ICT SMS for children with CD.
Primary Objective To evaluate the gastric emptying time of the protein hydrolysates PRO+CHO beverage in patients with a delayed gastric emptying and compare this with the gastric emptying time of healthy subjects (PrePro1) Secondary Objectives To…
To identify what might be the cause of the occurrence of diarrhea during the use of angiogenesis inhibitors sunitinib and sorafenib in patients with a malignancy.
The knowledge on PPI induced hypomagnesemia is restricted. For that reason, this study has two key objectives which investigate on the frequency and the causes of PPI induced hypomagnesemia:1. The investigation of the prevalence of PPI induced…
1) Prevalence of celiac disease in a Dutch cohort of adult type 1 diabetes patients. 2) Investigation of the long term complications of type 1 diabetes patients with concomitant celiac disease
Optimization of the supplementation of vitamins and minerals1. In patients who received a gastric banding for treatment for their morbid obesitya. Reduction of iron deficiencyb. Reduction of Vitamin B12 deficiencyc. Reduced Vitamin D deficiency2. In…
Aim: To investigate the performance of the new ESPGHAN diagnostic criteria for celiac disease in practice in different European countries.Primary aim: To evaluate whether the omission of biopsies in selected pediatric cases does result in certain…
We propose to perform a pilot study to examine the feasibility of studying the triangular association between: 1) amino acid metabolism (influenced by, amongst other factors, diet composition [e.g. energy intake, macronutrient intake, individual…
The aim of this randomized controlled trial is to determine the affect of screening on the Gastrointestinal symptoms (GIS) and Health Related Quality of Life (HRQL) in asymptomatic first degree relatives of CD patients. On the basis of the results,…
Objective: The primary objective is to determine if the dietary fructan-fiber inulin is applicable in PPIH. More specific, it aims to (i) improve the magnesium balance in cases of hypomagnesemic PPI users and (ii) to evaluate if the use of inulin is…
Correcting or preventing deficiencies of protein, by means of a protein supplement after a biliopancreatic diversion.
To evaluate immune function and (the susceptibility for) oxidative damage under the influence of long-term olive-oil based TPN use in patients without an active underlying disease and compare this with findings in healthy controls
To study the prevalence of HLA DQ2 or DQ8 gene locus and celiac disease in patients in which previously idiopathic intraepithelial lymfocytosis without villous atrophy was found.
1. Development of a prevention strategy for CD in children from high risk families for the disease by induction of oral tolerance to gluten;2. Identification of the immunological mechanisms involved in initiating the aberrant response to gluten…