12 results
To determine which advanced image enhanced modality is the most feasible for the detection of endometriosis lesions, with respect to the specificity and sensitivity of the investigated modalities. To determine which imaging modality reveals more…
Primary Objective:-Evaluate tumour detection sensitivity and specificity with the following image enhancement modalities:1 *narrow-band imaging*, (NBI)2 *near-infrared indocyanin green imaging*, (ICG)3 *5-aminolevulinic acid fluorescent imaging*, (5…
To investigate wether neo-adjuvant chemotherapy followed by cytoreductive syurgery and hyperthermic chemotherapy is feasible and reduces the number of irresectable patients with acceptable morbidity and mortality rates.
Our primary objective is to determine the incidence of EPS after kidney transplantation in patients previously treated by PD. We hypothesize that there is an increasing incidence of symptomatic and asymptomatic EPS after kidney transplantation.
Determining the feasibility and diagnostic accuracy in terms of sensitivity and specificity of intraoperative detection of peritoneal carcinomatosis of colorectal origin by intraoperative fluorescence imaging using the VEGF-targeting optical imaging…
Our primary objective is to determine the incidence of EPS after kidney transplantation in patients previously treated by PD. We hypothesize that there is an increasing incidence of symptomatic and asymptomatic EPS after kidney transplantation.
Our primary objective is to investigate the role of connective tissue growth factor (CTGF, a downstream mediator of profibrotic TGF-β1 activity) in peritoneal fibrosis and EPS. We hypothesize that soluble levels of CTGF and CTGF expression in the…
Main objective of this project is to establish the maximum tolerable dose (MTD) and recommended phase II dose of intraperitoneal irinotecan in patients with PC of colorectal origin, added to standard of care systemic chemotherapy. Other endpoints…
This study has been transitioned to CTIS with ID 2024-517152-34-00 check the CTIS register for the current data. The primary objectives are to explore the overall survival for the addition of intraperitoneal irinotecan (75 mg) to palliative systemic…
This study has been transitioned to CTIS with ID 2024-518570-13-00 check the CTIS register for the current data. Objectives of the phase II study (80 patients) are to explore the feasibility of accrual, the feasibility, safety, and tolerance of…
This study has been transitioned to CTIS with ID 2024-516265-37-00 check the CTIS register for the current data. The primary goal of the study is to establish the maximum tolerated dose (MTD) of intraperitoneal administration of irinotecan, added to…
Primary objectives: To assess the feasibility, accuracy and safety of preoperative SPECT/CT and intraoperative fluorescence imaging after administration of 111In-labetuzumab-IRDye800CW in patients with PC of colorectal origin who will undergo…