13 results
Primary aim: Frequency of identifying CTCs and their numbers in apheresis product before and after (during) treatment.Secondary aim: Prediction of response to therapy in different stages of NSCLC patient groups with the change in CTC numbers.
Identification of protein profile differences between laryngeal cancer of young and elderly patients. Secondary objective is to identify differences between protein interaction network in cancer and healthy tissue in young and elderly laryngeal…
The aim of this research is to gain a more detailed insight into the illness perceptions of patients with lung cancer. With this insight it is our aim to improve biopsychosocial care for these patients. Research question: What are the illness…
• To study the effect of treatment modalities immunotherapy (anti-PD1 or anti-PDL-1), and targeted therapy (crizotinib, gefitinib or erlotinib) on the size and diversity of lung carcinoma-specific T cell populations as measured by immune assays,…
The main objective of the study is to monitor the factors effecting success of PDT, namely oxygen, photosensitizer concentration and, light dose before and during illumination to gather data that can be clinically correlated and later implemented.
2.1 Primary objectives Primary objective is scientific research to study the additional effect of bevacizumab on hypoxia related parameters. 2.2 Secondary objectives a) To compare the efficacy of bevacizumab with pre-treatment obtained values of…
To investigate the newly developed method to study lung density changes using CT-scan, in a small patient population. The relationship between radiation induced lung density changes and dose distribution/tumor location will be investigated.
The primary objective is 1) to describe the long-term course of QoL in HNC patients and their informal caregivers and to identify cancer-related, personal, genetic, biological, psychobehavioural, physical, lifestyle-related, and social determinants…
The aim is to investigate whether it is feasible to perform a 12-weeks nutritional intervention study in NSCLC patients on PD-1 ICI, and to effectively assess their nutritional, immune, and microbial status, with the intention to use this…
To set up a biobank of prospectively collected tumor samples for genetic and immunological analysis, prior to and during IMA treatment.
The current study aims to recruit a greater number of lung cancer patients to measure tissue protein synthesis rates of non-small cell lung carcinomas and healthy lung tissue. The protein synthesis rates of healthy lung tissue will be compared to…
This is an exploratory study to assess the presence, specificity, type and strength of systemic and local specific cellular immune responses in patients with lung adenocarcinoma at different time-points during routine diagnostic work-up and…
Identify molecular differences in carcinogenesis of LSCC between younger and elderly patients through an integrated proteogenomic analysis of laryngeal tissue biopsies that could optimize personalized treatment of elderly patients in particular.