23 results
Primary Objectives:1) To determine immunogenicity of NIP vaccines in preterm infants when vaccinated according to the current Dutch NIP schedule and with rotavirus vaccine following the RIVAR study.2) To unravel the mechanism of immature host…
Determination of the seroprevalence and occupational risk factors for zoonotic transmission of hantavirus (including SEOV) and pathogenic Leptospira in professional groups that have high-risk contact with muskrats and/or coypu and the bycatch of…
1) To obtain insight into the age-specific seroprevalence (immunity) for selected vaccine-preventable diseases among adult refugees in order to determine the need for targeted vaccination campaigns among identified risk groups (age, country of…
To compare the number of responders to vaccination with the influenza virus vaccine and pneumococcal vaccine at different time points in treatment cycle of lenalidomide. Secondly to study the immune-response to vaccination, during treatment with…
Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…
To study if regular follow-up of PD patients with testing of their theoretical and practical knowledge (hereafter called *new type of follow-up*) can reduce the incidence of peritonitis, reduce the technique failure rate related to peritonitis, and…
This study has two goals:1. Investigate the cellular and humoral immune response of immune compromised travellers compared to the healthy traveller.2. Investigate the epidemiology of travel related infectious diseases in a population of dutch…
To screen two different formulations of the recombinant malaria vaccine PfLSA-3-rec, one adjuvated with aluminium hydroxide and one with Montanide Isa 720, by assessing the safety and immunogenicity (phase I) profile of each formulation in humans,…
To establish efficacy of pre-travel vaccinations by determination of protective serum antibody titres against hepatitis A, DTP and polysaccharide Vi of Salmonella typhi. To quantify health risks related to preventive actions and consequences of…
Primary Objective: • To determine the efficacy of 13vPnC in preventing a first episode of self-reported ILI.Secondary Objectives: • To determine the efficacy of 13vPnC in preventing a first episode of self-reported LRTI.• To determine the incidence…
Primary objective (parasitological): To induce protection against malaria by exposure to infectious mosquito bites under chloroquine prophylaxis. Secondary objectives (immunological): 1. To induce an effective immune response against natural malaria…
The primary objective of this study is to evaluate the effect of colostrum supplementation on the immune response after intense strenuous exercise.The secondary objective is to study the effect of intense strenuous exercise - and its possible…
The primary objective of this study is to investigate whether application of PRF® will reduce postoperative wound leakage, the necessity for allogeneic blood transfusions and the incidence of wound healing disturbances in patients undergoing…
To prove the efficacy and safety of ethanol lock solution in preventing catheter-related infections and subsequently venous thrombosis in children with a malignant disease who will have a tunnelled central venous catheter inserted.
Aim of the study is to assess the effects of supplemental parenteral L-alanyl-L-glutamine treatment on infectious, cardiac, cerebral, pulmonary and gastro-intestinal morbidity during the ICU- (Intensive Care Unit) and hospital stay in patients after…
The aim of the study is to evaluate whether the HBV serological response to Infanrix hexa vaccination, after administration according to the Dutch National Immunisation Programme, is sufficient according to World Health Organisation (WHO) standrads…
The primary study objective is to compare the rate of major CIED infections through 12-months post-implant between the TYRX envelope group and the control group.
To diminish the number of asthma exacerbations with the regular use of a bacterial lysate.
To obtain insight into the age-specific seroprevalence (immunity) for diseases included in the NIP of the Dutch general population.
The primary objective is to assess the (preliminary) effectiveness of a 4-week home-based exercise training program on an advanced cycle ergometer and the administration of nutritional supplements on preoperative aerobic capacity as measured by the…