66 results
1. to investigate the prognostic relevance of [18F]FLT uptake in resectable liver metastases of patients with colorectal cancer, in addition to existing prognostic indices with respect to disease-free survival; 2. in chemonaive patients, to validate…
Primary objective: - to test the hypothesis that an initial negative PET scan can be change in 4 months in a positive PET scan.Secondary objective:- to test the hypothesis that a negative PET scan is related to a less aggressive tumor with an…
The main objective of this study is to evaluate outcomes and resource needs of imaging and treatment following Primovist-enhanced MRI (PV-MRI) as com¬pared to ECCM-enhanced MRI (ECCM-MRI) and contrast-enhanced CT (CE-CT) in patients with a history…
Our primary objective is the development of an algorithm for liver tumour diagnosis using CEUS. This provides us with a more flexible, readily available and cheaper method without compromising specificity and sensitivity. We will compare diagnostic…
Primary Objective: Sensitivity, specificity and positive predictive value (PPV) for the detection and characterization of focal liver lesions using Gd-EOB-DTPA contrast or DWI with TRONSecondary Objective(s): 1) Differences between sensitivity,…
To identify new blood based protein biomarkers for the diagnosis of sepsis.
To identify predictive factors for response to sunintib treatment in patients with HCC. By discovering changes in pathways involved in HCC carcinogenesis due to sunitinib treatment in tissue/biomarkers and to correlate these changes to FDG-PET scan…
The trial aims to investigate whether procalcitonin measurements can reduce the amount of blood cultures in the ICU safely and cost-effectively.
This study aims to design a nomogram for the course of serum pro-calcitonin in burn patients. For this purpose, a new, sensitive assay will be used. It is expected that the nomogram will help to differentiate between patients with a systemic…
The aim of the present pilot study is to assess whether percutaneous optical spectroscopy can serve as a novel tool for tumour response evaluation in patients with unresectable colorectal liver metastases receiving first line systemic therapy.
To gain insight in the risk of transmission of tick-borne micro-organisms Borrelia, Ehrlichia, Rickettsia and Babesia to humans and to gain insight in risk factors.
The aim of the study is to improve the diagnostic tools of spontaneous bacterial peritonitis.The primary aim is to evaluate the use of dipsticks as bedside diagnostics compared to the current standard polymorphonuclear leukocyte count in identifying…
The primary objective of the present study is to assess the agreement rate of Scintimun® Granulocyte and 99mTc-WBCs with regard to the diagnosis of infection/inflammation by immunoscintigraphy, based on the evaluations of three blinded and…
The aim of this study is to assess the clinical value of 99mTc-mebrofenin SPECT for the measurement of liver functional volume in patients planned for liver resection, in comparison to CT-volumetry. Furthermore, the significance of liver volume in…
Aim of this study is to assess the value of cholangioscopic directed biopsies versus brush cytology in differentiating between malignant and benign biliary strictures. Determination of tumor markers to improve early diagnosis of malignant biliary…
Validation of MRI with Primovist® for differentiation of FNH and HCA.Do imaging and histological outcome correlate?Is it possible to use MRI with Primovist® (as gold standard) in the diagnostic work-up of FNH and HCA?
The purpose of this study is to compare routine multiphase (4-phase) CT images of the liver with ultra-fast total volume multiphase (12-phase) dynamic CTP of the liver for the detection of small and occult liver metastases and for local tumour…
For further details see - Protocol section: 2 - Aimo Assessment of the accuracy of the FCH PET/CT scan in diagnosing HCC. o Assesment of radical surgical resection, using the FCH PET/CTscan.o Assesment of recurrence after surgical resection, using…
To make an efficacy evaluation of Gadolineum Ethoxybenzyl (Gd-EOB) DTPA-enhanced MR-imaging (Gadoxetic acid, Primovist, Bayer Schering Pharma, Berlin) and Respiratory Triggered Diffusion Weighted Imaging (DWI) for the detection and characterization…
To evaluate the outcome of FISH testing with a set of biomarkers with regard to the prognostic value and the diagnostic accuracy for both sporadic cholangiocarcinoma and PSC related cholangiocarcinoma. Subsequently we want to develop a valid…