66 results
This study has been transitioned to CTIS with ID 2024-516486-36-00 check the CTIS register for the current data. Part A: To acquire an optimal pharmacokinetic model of [68Ga]Ga-FAPI-46 by which simplified methods to quantify [68Ga]Ga-FAPI-46 PET…
To determine the accuracy with which patients with probable or proven invasive pulmonary aspergillosis and neutropenic controls can be discriminated from each other, as measured by the values of the sensitivity, specificity and accuracy.
Primary objective:The objective of this randomized phase 2 study is to demonstrate efficacy of RE in terms of PFS in colorectal cancer patients with liver-only metastases who are candidates for palliative systemic treatment with capecitabine plus…
Over recent years, post-processing software has become available that allows co-registration of pre- and post-ablation CECT. This allows three-dimensional quantitative assessment of ablation margins. Such quantification of ablation margin would…
To assess the feasibility of CT based 3D preoperative resection planning for hepatectomy and postoperative resection confirmation through image fusion of pre- and postoperative 3D CT reconstructions.
To study the impact of addition of the GAAD score to imaging in patients with chronic liver disease eligible for HCC surveillance.
1. To describe mitoPO2 in clinically admitted critically ill septic patients receiving fluid therapy (consisting of crystalloid, albumin and/or red cell transfusion).2. To describe the effects of fluid therapy on mitoPO2 and on other physiological…
To evaluate our proposed SMS protocol in high-risk patients and compare it to a bi-annual US screening.
Our proposal builds on 12 years of sustained EU funding, a consortium covering 11 European countries and 27partners (with non-EU sites in African and two Asian populations to provide a global perspective) and our cuttingedge new research, which has…
The primary objective of this study is to determine the accuracy of the delta PCO2 (PaCO2-tcPCO2) and delta PO2 (tcPO2 -cPO2) levels for the detection of sepsis. The secondary aims are to determine the factors that influence delta PCO2 and delta PO2…
The objectives of this study are1)To asses the sensitivity, specificity, positive and negative predictive values of HIV, HBV, HCV, syphilis and creatinine screening tests performed on dried blood client-collected samples at home, as compared to…
The primary objective of this study is to demonstrate the clinical utility of the addition of per oral cholangioscopy (POCS) to standard ERCP with brushing cytology for diagnosis and early detection of cholangiocarcinoma in patients diagnosed with…
The primary objective of this study is to validate the accuracy of FebriDx to discriminate between viral and/or bacterial respiratory infections. Besides this, the predictive value (negative predictive value (NPV) and positive predictive value (PPV…
Multimodality Preoperative Evaluation of lymph nodes of perihilar cholangiocarcinoma - a pilot study
The primairy aim of this pilot study is to evaluate the feasibility of systematic survey by EUS-FNA/FNB.
To compare the sensitivity of ERCP brush cytology between standard RX cytology brush and Inifinity brush in patients with pancreatobiliary strictures suspicious for malignancy.
Identification of host biomarkers, being membrane bound proteins, on both neutrophils and CD64 expressing cells, that have discriminatory difference in concentrations.
The aim of this study is to determine the added value of low-dose CT and PoC-PCR in the diagnostic workup of patients with CAP hospitalised to non-intensive care unit (ICU) wards in minimizing selective antibiotic pressure while maintaining patient…
Observational pilot study to investigate NGS as a reliable method to identify sepsis in neonates. NGS is proposed as a method to improve clinical identification, diagnosis and stratification of neonatal sepsis and provide basis for a more adequate…
The aim of the study is to improve the diagnostic tools of spontaneous bacterial peritonitis.The primary aim is to evaluate the use of dipsticks as bedside diagnostics compared to the current standard polymorphonuclear leukocyte count in identifying…
The main objective of this study is to determine the optimal dose and timing of the ICG injection by optimizing signal-to-background ratios in patients with colorectal liver metastases pretreated with chemotherapy to improve radical resection rates…