38 results
We have developed the TES program, which involves Targeted selection and Enhanced care, delivered on the basis of Stepped care (TES). The primary study aim is to evaluate the effectiveness of the TES-program compared to usual care in reducing…
The primary objective of the research is to measure the effect of a 3 week prehabilitation program on the postoperative complications in patients with an anaerobic threshold of <11 ml/kg/min who*ll undergo elective coloretal surgery for…
This study examines the effect of systematic geriatic screening, via a geriatric oncology care module and geriatric interventions, on the quality of life of patients aged 70 years or older with colorectal carcinoma. We also examine whether…
Our primary objective is to study the effect of perioperative intravenous supplementation of omega-3 fatty acids on the perioperative inflammatory response compared to a saline control in patients undergoing surgery for colon cancer.
Objective of this study is to determine the prevalence of vitamin B12 deficiency among patients who underwent esophagectomy with GTR. The following specific research questions heve been defined:- What is the prevalence of vitamin B12 deficiency in…
The effect of radiotherapy on glucose metabolism in patients with rectal cancer; a feasibility study
Primary objective:Effect of preoperative radiotherapy on insulin resistance in rectal cancer patients.Secondary objectives:Effect of preoperative radiotherapy on plasma oxidative stress parameters.
Primary objective: Adherence in patients starting the use of capecitabine and the influence of patients attitudes and side effects on adherence.Secondary objective: The second part of this study contains 1) a validation study of the adherence…
This study will contribute to improving quality of care for cancer survivors, since sexual problems seem to be profound but not always discussed with patients. Patients are now often insufficiently informed and do not know how to interpret their…
The effect of the dipeptide alanyl-glutamine, intravenously or enterally and perioperatively given, on postoperative insulin resistance in colon cancer patients.
Evaluation of the effectiveness of a new system HD2/NBI2 to improve the detection of colorectal neoplastic lesions during colonoscopy in comparison to the former generation with currently highest share of the installed base (nonHD-nonNBI system i.e…
To investigate whether stem cell sparing radiotherapy results in a lower risk of dry-mouth syndrome than current standard treatment technique.
1) Study the chemopreventive potential of 5-ASA and UDCA in UC by evaluating the effect of treatment on ACF number, size and rate of dysplasia, relative to the placebo group. 2) Gain mechanistic insight into the chemopreventive properties of 5-ASA…
1.What are ulcerative colitis patients* understanding of their risk of colon cancer and the benefit of colonoscopy?2. What is ulcerative colitis patients* threshold of cancer risk before accepting colectomy in the setting of dysplasia?3. What are…
The primary objective of this study is to evaluate the prevalence and risk of advanced colorectal neoplasia in asymptomatic non-PSC post-liver transplant recipients compared to an age- and sex matched general population.Secondary Objectives- To…
We will start a Dutch prospective cohort study of colorectal cancer patients. In this cohort we will assess the intake of dietary supplements, dietary intake and life style factors of colorectal cancer patients. We will study if and how those…
The primary objective of this second phase study is to estimate the occurrence of anastomotic leakage when the C-seal is used.Secondary objectives are:* Feasibility of applying the C-seal, especially considering the improved attachement to the…
This study will be performed to test the predictive value of the GFI, the VES-13 and the timed *up and go* test compared to components of PACE in elderly patients of the age of 70 years and above undergoing surgery for a solid tumour.
1) Study the chemopreventive potential of 5-ASA and UDCA in UC by evaluating the effect of treatment with these agents on ACF number, size and rate of dysplasia. 2) Gain mechanistic insight into the chemopreventive properties of 5-ASA and UDCA by…
The main objective of this study is to investigate whether quality of life can be improved by personalised and timed guidance, and/or use of the peer-support platform; as provided by a patient-centred mobile application.
The primary objective of study is to assess the feasibility (participation rate, reasons for non-participation, adherence/compliance, dropout rate, reasons for dropout, adverse events, patient motivation, patient appreciation, and therapist…