110 results
1. to investigate the WavSTAT optical biopsy system by collecting fluorescence spectra of non-dysplastic and dysplastic Barrett mucosa and correlate these to the histology. The integrated optical/physical biopsy forceps will ensure spot-on…
Primary Objective: To evaluate whether a single intravenous alfentanil bolus (7.5 mcg/kg) has a clinically significant analgesic effect in clinical patients who undergo an elective CT-colonography compared to placebo. We have defined a clinically…
To compare a new endoscopic brush device with conventional brush cytology and compare the amount of cells obtained by the two different brushes
We want to estimate the additional value of perfusion CT over the 4 phase contrast CT. Furthermore, we want to correlate measurements of perfusion CT (parameters) to histopathological properties of the tumor.
To establish the safety and preliminary efficacy of Check-Cap*s P1 Capsule System in patients eligible for CRC screening
Assessment of the detection of neoplastic lesions in patients with longstanding ulcerative colitis, using different endoscopic imaging techniques: A: Chromo-endoscopy, methylene blue 0.1% (HDTV Olympus)B: HDTV Olympus colonoscopes and NBIC: Chromo-…
Primary, to determine whether staining of the gastric mucosa increases the number of detected (pre)malignant foci of diffuse type gastric cancer, in individuals from families with FDGC as well as dysplastic, adenomatous and early intestinal cancers…
In patients undergoing surveillance endoscopy for Barrett;s oesophagus or work-up and treatment for early neoplasia in Barrett's oesophagus we will evaluate the N-Vision pVLE system for the following items:1) feasibility of the system2) the…
This clinical trial will evaluate the inter-observer agreement of a simple, consensus driven NBI classification system of surface patterns and its ability to differentiate dysplastic vs. non-dysplastic BE in patients undergoing BE screening or…
To study the feasibility of the endoscopic guided placement of gold markers in patients with esophageal tumors and to determine the utility of the markers tumor delineation and for positional verification during treatment.
To develop an MR scanning protocol for pancreatic cancer
The primary objective is to determine the feasibility of the in vivo sentinel node procedure in patients with colon carcinoma, during open and minimal invasive surgery.The secondary objective of the study is awareness and knowledge of (non)sentinel…
Primary Objective: Description of the 1-year overall survival after chemo-radiation therapy with or without panitumumab in irresectable carcinoma of the oesophagus. The control arm is used to validate whether the historical cohort used for…
Study phase 1: In patients with BO undergoing work-up endoscopy for early neoplasia, we aim to develop a classification to evaluate fluorescence spectroscopy of neoplastic and non-neoplastic lesions in Barrett epithelium, as used in phase 2.Study…
1. Study the overall miss rate of polyps detected with the third eye retroscope compared to standard colonoscopy.2. Study the overall miss rate of adenoma detected with the third eye retroscope compared to standard colonoscopy.3. Analyze the time…
the investigation and evaluation of certain serummarkers for inflammation and tumoractivity during the followup of colorectal neoplasms, and the applicability of these markers during the followup of these patients or the evaluation of the effect of…
The aim of this study is to investigate whether DWIBS may be an appropriate technique for colorectal cancer screening.
In patients with BO undergoing surveillance or work-up endoscopy for early neoplasia, we aim to evaluate if EQMI, consisting of ETMI combined with pCLE, increases the accurary of detecting early neoplasia (study phase 1). In addition, we aim to…
Primary objective: to investigate the day-to-day shape variation of the CTV in rectal cancer patients in order to determine adequate PTV margins for radiotherapy treatment.Secondary objectives: to investigate the influence of bladder and rectal…
The aim of this study is to investigate whether DWIBS is appropriate for colorectal cancer screening.