59 results
The purpose of this prospective study is to evaluate the value of 18F-FDG PET/CT and CT for preoperative regional N staging of bladder cancer and to verify the results by comparison with histopathological analysis, the gold standard.
To assess the feasibility and safety of intraoperative dual-modality imaging in patients with renal cell carcinoma with Indium-111-DOTA-girentuximab-IRDye800CW. Secondary objectives are to assess how intraoperative fluorescence imaging results…
ObjectivesPrimary objective: To assess the added value of FDG-PET and 89Zr-Girentuximab-PET results measured at presentation to predict time to progression under watchful waiting in patients with good or intermediate prognosis mccRCC who are…
The identification of RCC is crucial for planning possible surgery and treatment. The aim of this study is to investigate the safety, tolerability, radiation dosimetry, as well as the diagnostic performance of 89Zr-girentuximab PET/CT in patients…
Primary objective: To compare the cancer detection rate of CEUS targeted biopsies with the cancer detection rate of mpMRI targeted and systematic biopsies. Secondary objective: To characterize the tumors detected by the different biopsy schemes in…
The primary objective of this study is to compare diffusion MRI derived parameters with the histological categorization of kidney tumours.
The objective of this study is to improve the treatment of prostate cancer. By more accurately diagnosing both clinically significant and insignificant prostate cancer, treatment strategies will improve. This accounts for active treatment like…
To evaluate the clinical role of MRI/TRUS fusion target biopsy on prostate cancer detection, compared with other target biopsy strategies, in men with a persistent clinical suspicion on prostate cancer and at least one negative TRUS guided biopsy…
To validate a diagnostic panel existing of MRI, CEUS, and FNA, which can differentiate benign pathology from malignant pathology of complex renal cysts.
To quantify renal tumour motion using MRI.
To establish in vivo sensitivity and specificity of OCT in the diagnosis of Upper Urinary Tract Urothelial Carcinoma
To identify what might be the cause of the occurrence of diarrhea during the use of angiogenesis inhibitors sunitinib and sorafenib in patients with a malignancy.
The 1st main objective is to collect detailed quantitative data on the everyday management of mRCC in the Netherlands, the clinical outcome of this management, as well as the resulting quality of life and financial costs. Treatment selection for…
To analyse the concentration catecholamines in thrombocytes of patients with clear cell renal cell carcinoma and low grade neuroendocrine tumours. To compare these concentrations with the concentrations catecholamines in thrombocytes of healthy…
Primary Objective:to clinically use and validate the optimized Raman probe in a patient database in order to differentiate between benign and malignant bladder lesions in vivo.Secondary objective:to develop an algorithm to predict tumor grade in…
2.1 Primary objective: To improve PCa detection rate with quantification, compared with subjective CEUS interpretation and known numbers in literature. 2.2 Secondary objective: To compare quantification results with tumour differentiation grade (…
At the Atrium Medical Center Heerlen, in 2005 a study has been initiated with the aim of developing a new diagnostic tool for patients with prostate carcinoma. By using flow cytometry, PSA can be measured in activated monocytes, naming macrophages.…
To determine the relation between tumor tissue phosphoproteomic profiles and progression-free survival (PFS) in patients with advanced RCC
The objective of this study is to record and evaluate an elastography guided biopsy used in routine clinical procedure and to validate its value with respect to improved prostate carcinoma visualisation and detection. The intention is to represent…
To assess whether a change in BMD as detected big DXA (gold standard) is comparable with the decline measured by the achilles method