33 results
The aim of the current study is to:1. Determine the incidence of CIN after introduction of preventive measures.2. Describe changes in the course of biomarkers serum creatinine, microalbumin and microglobulin related to intravenous ICM administration…
2.1 Primary Objective: To evaluate the feasibility of RenalGuard for diuresis-guided fluid replacement therapy (ability to match in and output) (time to desired diuresis>200ml/hour) To evaluate the safety of forced diuresis and fluid…
To investigate the incidence of CIN in three hospitals where patients are treatedaccording to the current guidelines, to identify the prediction risk factors and toobtain blood and urine samples that will allow future identification and evaluation…
The purpose of the study is threefold. First, to describe the course of quality of life after renal transplantation and to identify predictors of (un)succesful adjustment. Second, to investigate intra- and interindividual differences that influence…
(1) to establish the effect of adding amiloride to lithium- treatment on the progression of renal insufficiency in patients with lithium- nephropathy (2) to answer the question whether adding amiloride to the use of lithium has the same effect as…
To investigate if home-hydration is a non inferior alternative for in-hospital hydration in the prevention of Contrast Induced Nephropathy in high risk patients.
The objective of the study is to evaluate the safety and efficacy of eculizumab to prevent AMR in sensitized recipients of living donor kidney transplants requiring desensitization therapy.
To study whether the existing eGFR cut-off levels for preventive hydration of < 45 ml/min or between 45-60 ml/min in combination of other comorbidity at risk of CIN can be safely lowered to an eGFR < 30 ml/min, regarsless of the…
The objective of our study is to investigate the relative (cost-)effectiveness of the two Dutch guidelines in patients receiving intravenous iodinated contrast medium during computed tomography. A cohort study will compare both screening methods to…
Study whether chloroquine as comedication results in a better respons on Hepatitis B vaccination in non-responder dialysis patients.
Primary objective: to compare the effect two immunosupressive therapy regimens on GFR estimated by iohexol clearance at week 52 post kidney transplantationSecundary objective: to compare the safety and efficacy profiles of the two immunosupressive…
The primary objective of this study is to compare Arm 1 with Arm 2 with regard to incidence of new onset diabetes Mellitus as per the American Diabetic Association criteria at any point up to 24 weeks after kidney transplantation.The secondary…
Evaluation of the rise in serum creatinine and the incidence of CIN following angiography in patients treated with a short hydration regime during 1 hour with sodium bicarbonate compared to a hydration regime with saline during 6-24 hours.
1. to determine the feasibility and acceptability of an e-supported lifestyle coaching program and2. to assess the effects of personalized lifestyle support in patients with insulin dependent type 2 diabetes mellitus immediately after 12 weeks and…
Objective of this study is to compare 1-year garft survival after hypothemic machine perfusion with oxygentaed perfusion solution versus static cold storage of extended criteria kidneys from DBD donors.
This study has been transitioned to CTIS with ID 2023-504884-17-00 check the CTIS register for the current data. The main goal of this study is to find out whether finerenone in combination with either an ACE inhibitor or an ARB can reduce the…
To study the renoprotective effect of potassium supplementation in patients with CKD (stage 3b or 4 or estimated glomerular filtration rate [eGFR] 15 - 44 ml/min/1.73 m2).
The primary objective of this study is to investigate the effect of lifestyle and dietary habits on outcomes in patients with type 2 diabetes mellitus.
To examine the effects of mono- and combination therapy with linagliptin and empagliflozine on renal hemodynamics
To compare the effect of a sevoflurane based anesthesia versus a propofol based anesthesia on acute rejection and outcome in recipients of living, DCD and DBD donor kidneys.