296 results
The primary goal of this research is to develop a pharmacokinetic/pharmacodynamic (PK/PD) model for sunitinib and pazopanib in patients with metastatic renal cell carcinoma, so that the possible use of biomarkers can be tested as predictors for the…
The primary objective is to evaluate the feasibility of early therapeutic effect evaluation by performing early follow up imaging after percutaneous MR-guided cryoablation of pT1a renal cell carcinoma. Secondary objective is to assess the outcomes…
to study the effect of everolimus (vs. mycophenolate) on dyslipidemia, ectopic fat accumulation, and cardiovascular function against a common calcineurin inhibitor (CNI) background.
To assess renal sympathetic reinnervation in the kidney allograft by 123-I-MIBG scintigraphy.
To evaluate the accuracy and adverse events of combined use of minimal invasive optical coherence tomography (OCT) to differentiate normal tissue from (different types of) malignant tissue in kidneys.
The objective of this study is to identify potential predictors of renal fluid responsiveness.
Compare succesfull creation and usage of the buttonhole track for hemodialyses, created by either the conventional way or with the supercath
The objective of this pilot study is to investigate the association between hemodialysis-associated changes in tryptophan levels and changes in symptoms of depression and fatigue, and the temporal dynamics between depression and fatigue.
Primary Objective: Primary endpoints will be renal (ERPF, GFR and FF) response to angiotensin II after low and high sodium diet in formerly preeclamptic patients compared to healthy controls. Secondary Objectives: Secondary endpoint will be systemic…
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
The primary objective of the study is to evaluate the feasibility of 89Zr-bevacizumab PET imaging as a biomarker before and during treatment with everolimus in patients with metastatic RCC. 89Zr-bevacizumab PET imaging will be regarded a promising…
Primary Objective: Our primary objective is to investigate the effect of NAC on H2S levels in plasma in different patient groups, i.e. healthy volunteers, CKD patients, and dialysis patients. We hypothesize that there is an increase in H2S levels…
Ascertain feasibility, study burden, between-subject and within-subject variability of automated RH-PAT measurements in paediatric renal transplant recipients. Comparison of adipokines and inflammatory profiles in renal transplant recipients and…
Compare usual care in patients with treatment resistant heart failure with additional ultrafiltration by peritoneal dialysis.
To find out if there is a protective effect of postconditioning on ischemia reperfusion-injury in kidneytransplantation.
To dermine whether the endothelial glycocalyx is damaged by ATG therapy.
To investigate the Ertapenem plasmaconcentration time curves in a dosingscheme of three administrations per week after hemodialysis in patients with end stage renal disease depending on hemodialysis. To find a pharmacokinetic model to describe…
Measuring the effects of light therapy during hemodialysis on objective en subjective sleep parameters, sleepiness during dialysis, mood and melatonin rhythm. De results of this pilot study can be used to design a larger study on light therapy in…
The aim of the study is to observe whether microcirculatory perfusion follows the decrease in preload caused by hemodialysis in a population with an intact and a disturbed microcirculatory autoregulation.
The effects of kidney transplantation on circadian rhythm. Focus on sleep and cardiometabolic risks.
Primary Objective: - What influence has kidney transplantation on (recovery of) melatonin production?Secondary Objective(s): - Is recovery of melatonin rhythm after kidney transplantation related to improvement of other circadian rhythms, e.g. body…