80 results
1. To assess reference values of a pre-defined set of biomarkers for AKI in *surgical* infants with normal kidney function.2. To determine the incidence of AKI in critically ill infants, according to pRIFLE criteria.3. To evaluate the sensitivity…
Primary Objective: The main objective of this study is to determine whether MRI and ultrasound are capable to distinguish the existence and extent of microcysts in a Dutch population of lithium treated patients.Secondary Objective(s): to determine…
Primary Objective: To calibrate the measurement of ECFV by 125I-iothalamate in subjects with a GFR <60 ml/min and GFR <30 ml/min, using an accepted measurement of ECFV: distribution volume of Bromide.Secondary Objective(s): To…
To determine the value of cystatine-c based renal function assessment in adults with spina bifida when compared to the golden standard of 24-hours urine collection.
AKINESIS is a multi-center prospective, uncontrolled clinical study to assess the utility of a plasma NGAL test (Triage® NGAL Test) and a urinary NGAL test (ARCHITECT® Urine NGAL) in predicting worsening renal function in patients presenting with…
This study has two main objectives:• to evaluate the prevalence of dRTA in pSS using the urinary acidification test with FF and compare this against the gold standard test with AMCL.• to evaluate whether a low BMD is more prevalent in patients with…
Primary Objective: Mapping the consequences of a congenital monokidney on kidney function for children with MCKD.Secondary Objective(s): - Giving recommendations about follow-up for children treated with nephrectomy for MCKD.- Defining better blood…
Primary objective:-To diagnose acute pyelonefritis with MRI in comparison with the reference standard: DMSA scanning.Secondary objectives:- To determine whether MR-diffusion weighted imaging (DWI) has additional value in the imaging of…
Serum hepcidin levels are elevated in hemodialysis patients and may contribute to functional iron impairment and thus to ESA-resistance. Kinetics of hepcidin in hemodialysis patients has not been studied in detail. This study is designed to provide…
Primary objective:- To determine the clinical efficacy of multiple doses of 177Lu-DOTA-cG250 at MTD in patients with advanced renal cancer using RECIST criteriaSecondary objectives:- To determine the toxicity of the treatment as defined by NCI…
The primary objective of the study is to evaluate the feasibility of 89Zr-bevacizumab PET imaging as a biomarker before and during treatment with sunitinib or bevacizumab plus interferon in patients with RCC.
Assessment of the effect of kidney-pancreas transplantation in diabetic nephropathy patients on microvascular alterations using orthogonal spectral polarization and correlate this effect with markers for endothelial cell dysfunction and fibrosis
The objective of this study is to determine the accuracy of the Cockcroft-Gault and the MDRD formula as estimators of GFR in geriatric patients. Some other new methods for daily practice will be investigated as well (see primairy parameters).
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To investigate site and distribution of sentinel nodes in clinically non metastatic kidney cancer.
Assessment of microvascular alterations using orthogonal spectral polarization and correlate this with markers for endothelial cell dysfunction, fibrosis and histology in patients with renal function impairment who will undergo renal biopsy and…
Aim of the present study is to test the hypothesis tha during inflammatory episodes there is a decline in lean body and fat mass and that this results in an increase in extracellular volume in dialysis patients because dry weight is not or…
Our primary objective is to determine the incidence of EPS after kidney transplantation in patients previously treated by PD. We hypothesize that there is an increasing incidence of symptomatic and asymptomatic EPS after kidney transplantation.
The statistical analysis will evaluate the correlation of Baseline NGAL and BNP levels -alone and together - with the clinical outcomes of hart-failure (HF-related adverse clinical outcomesthrough Day 30 and Day 90. The cut-off and estimated…
This study is aimed at the development of a noninvasive method which leads to a more accurate and precise estimation of the creatinine clearance when compared with the Cockroft-Gault, MDRD or Nankivell formulas and taking the 24-hour urine…