93 results
We aim to investigate whether a relation between intestinal microbiota composition, mucosal integrity and translocation of bacteria into adipose tissue of the affected eye is related to the severity of Graves orbitopathy.
To measure the quality of peripheral visual field in healthy volunteers and the effect of different corrective lenses on the peripheral visual field.
Primary objectives1) To clarify which components of spatial remapping are impaired after damage to the posterior parietal cortex.2) To correlate spatial remapping abilities with scanpath quality in visual search.3) To examine whether different…
The objective of this study is to investigate the use of retinal oximetry in children, between five and seventeen years of age, with (vitreo-) retinopathies and oxygen-related diseases of the retina by means of an Oxymap T1 fundus camera.
The major goal of this study is to develop a systematic and stepwise approach for dry eyes. First, it will be evaluated whether Tes glasses are a diagnostic tool for dry eye diseases. Second, it will be evaluated or it can make a distinction between…
To study the efficiency of visual information processing in patients with retinal disorders.
The primary objective of this study is:- To determine the potential difference in MT and RNFLT between treated and untreated patients with anisometropic or strabismic amblyopia. Secondary objectives are:- To determine the potential differences in MT…
Our objective is to find predictive biomarkers for disease progression in RVCL-S, a monogenetic small vessel disease, and to dissect disease mechanism to identify new treatment targets to improve health for RVCL-S patients, which may also serve as…
Objective: To determine the incidence of asymptomatic oral and corneal HSV-1 shedding.
Development of a laboratory assay
The aim of this study was to test these biomarkers of NO in glaucoma patients both with and without tinnitus. The objective was also to replicate findings from a previous study performed in Amsterdam, a collaboration between our research group and…
To collect data in order to create a registry that can be used for research in PXE, partly with an international questionnaire, and to measure PPi, ENPP1 activity, anti-retinal antibodies and cytokines, and retinal calcification in all patients…
To investigate whether mutations in genes associated with lipid metabolism are a risk factor for retinal pathology such as the early formation of drusen
To determine whether functional and/or structural retinal biomarkers or circulating biomarkers are able to differentiate people with mild cognitive impairment (MCI) within the type 2 diabetes (T2D) population (this we will be able to do in the…
Connection Interrupted: Genetic causes and clinical characteristics of hereditary optic neuropathies
The goal of this study is to identify the genetic causes underlying hereditary optic neuropathies and establish genotype-phenotype correlations. This will lead to more reliable prognosis predictions, better genetic counselling and hopefully form a…
Pre-pilotfase:To optimize procedures and cost efficiency in the design of the pilot phase, we address the following questions:1. Which systemic factors are most useful to monitor AMD supplement intake?2. Can these factors be measured by finger prick…
The aim of this project is to investigate associations between visual system functioning, ADHD, and the circadian rhythm. We will also investigate the effects on the functioning of the visual system of commonly used treatments for ADHD and related…
To demonstrate that cone density can be reliably and accurately measured after vitrectomy for RRD split fovea and for RRD macula-off.
The goal is to study the genetic background of childhood glaucoma in the Netherlands. We aim to study which mutations play a role in the pathogenesis of childhood glaucoma in the Netherlands and their prevalence. We will study the genetic mutations…
Systems biology is an interdisciplinary approach that systematically describes the complex interactions between all the parts in a biological system, with a view to elucidating new biological rules capable of predicting the behavior of the…