23 results
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
The aim of this study is to investigate whether the risk and severityof retinal detachment are related to skin autofluorescence (AF).
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
Assess the quality and applicability of smartphone assisted and handheld fundus photography, compared to standard fundus photography. Photographs will be taken in non-mydratic and mydriatic conditions.
The aim of this study is to determine if retinal defects and detachments can be detected by fundus photographs taken with the Optos 200Tx fundus camera.
The aim of the study is to measure RT (central, peripapillary and peripheral) in normal subjects and study the posibillity to reduce the variabillity of this measurements by normalisation. Futhermore, correlation of RT with axial lenght, gender and…
To measure the test-retest and inter-chart reliability of the Dutch version of the Radner reading chart in an older population with maculopathy.
By observing several visual aspects in a large patient population we would like to obtain more information about the best time of surgical intervention (primary study group). 80% of the patients need only one surgical intervention to obtain an…
Objective: To investigate whether binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants or not.
To confirm the previously reported negative predictive value of urine NTproBNP for ROP in large, multi center cohort of preterm infants.
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
To improve imaging of sub-RPE structures with OCT.
A pilot study to prove the validity of the Macubit teste, the Macuscope Test, and the measurements of the retina with the OCT, to test for early functional, and structural loss in the central part of the macula in patients at risk for developing…
To investigate visual function recovery after surgery for foveal splitting RRD.
The goal of this study is to characterize the natural course of IRDs that can potentially be modulated by future therapy. Second, this study aims to understand the relationship between various structural and functional biomarkers in potentially…
To compare, the perifoveal microvascular changes (non-perfusion areas) in the deep capillary plexus layer between Behçet patients with and without ocular involvement and control subjects, using OCT-A.
To visualize the different components of RAP lesions with high resolution Doppler OCT, and to evaluate the change in intra- and transretinal flow after treatment.
Main objective: To map the natural course of the visual and hearing deterioration in Usher Syndrome type 2 for upcoming genetic therapy studies.Secondary Objective 1): To determine a. the necessary type of (combined) examinations, b. the sample size…
To report the natural history of retinal degeneration in patients with biallelic mutations in the USH2A gene; to identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in USH2A-related retinal…
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.