557 results
The following research questions are formulated:A. Does exposure to cannabis (THC) result in an increased dopamine response in the striatum (as measured with PET)? And does cannabis use lead to an increase in psychotic experiences or symptoms?B. Do…
The primary objective is to investigate whether a brief (10+2 sessions) Cognitive Behavioural Therapy (CBT) program can (postpone or) prevent the onset of depression or anxiety disorder in an ultra high risk sample of 8-18 year old children of…
Overall Aim - The TRAILS study group*s overall aim is to chart and explain the development of mental health from preadolescence into adulthood, both at the level of psychopathology and the levels of underlying vulnerability (and resilience) and…
The present study primarily focuses on differences between children with behavioral disorders and children with autism spectrum disorders and normal controls. Different aspects of empathy will be assessed: neurobiological, psychological, behavioral…
Study A: Show BP patients similar progression in brain volume change compared to schizophrenia patients. If so, can the progressive change in BP patients also be explained by genetic factors?Study B: Show BP patients and their non-bipolar cotwins…
My research proposal, therefore, will focus on the changeability (plasticity) of the ability to experience positive emotions in response to daily events (natural rewards), as a first step towards novel (preventive) interventions. The main question…
The main question in the study isHow do moderately preterm infants and their parents differ from term, as well as extreme preterm infants in (a) development and self regulation skills of the infants, (b) interaction patterns and relationship between…
De primary objective is to investigate the relationship between serum levels of before mentioned biochemical parameters (amino acid profile and monoaminergic parameters and the neurotrophic proteins BDNF and S-100B) and the symptomatology at…
This study aims to investigate the possible differences in speech characteristics of people with schizophrenia and autism, compared to people without a psychiatric diagnosis. Also, the possibility of creating a new means of improving the…
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
The primary objectives of the present study are: 1) to study factors involved in the transition from risky non-dependent cannabis use to cannabis dependence, 2) to study the three-year natural course of cannabis dependence, including factors…
Study ObjectiveTo determine whether alprazolam, a registered anxiolytic non-selective benzodiazepine, can reduce the autonomic temperature increase induced with social stress in healthy men. Secondary objectives are to determine whether alprazolam…
Our objective is to test the following hypotheses : - Hypothesis 1 (part 1 of the study): The stress reduction intervention has beneficial effects on subjective maternal emotional well-being, on objective maternal stress system measures (i.e., HPA-…
The main objective of the present study is to test 1) whether paranoid anxiety moderates the relation between rejection and aggression, and 2) whether social anxiety moderates the relation between rejection and withdrawn behavior.
(1) to determine the psychiatric status (ADHD and ODD/CD) for the second time in participants from ADHD and control families about 5 years after the first assessment. The participants will be between 10 and 23 years of age now; (2) to determine the…
Objective of the study: The main objective of this study is to investigate the influence of different genetic mechanisms (risk genes, CNVs and gene expression profiles) in ASD and to study the relation between the genetic heterogeneity and specific…
The main goal of the study is to examine the predictive value for treatment outcome ofneurophysiological indices of two aspects of cognitive control in abstinent cocaine dependent patients: Error-processing and attentional control (respectively…
The current study employs functional magnetic resonance imaging (fMRI) to investigate the auditory and limbic areas in tinnitus patients by means of innovative analysis methods that permit the assessment of functional interactions between brain…
The aim of this study is to examine if an increased number of awakenings in PTSD is PTSD dependent or trauma dependent. Furthermore, the purpose of the study is to examine if the nocturnal excretion of cortisol is increased.
Objective: To determine whether specific genetic variations, such as variable tandem lengths of repeats and polymorphisms, in certain genes are more prevalent in people with panic disorder than in controls. To determine whether contribution of these…