557 results
1) Assess the whole genome sequence (WGS) and clinical profile of the MPX families to identify how rare and common genetic variants interact to produce shared versus distinct NDDs and clinical features in individuals, or different combinations of…
The objectives of the current study, are to assess in a sample of remitted recurrently depressed patients over a 20-year follow up period: the long-term effects of PCT; the long-term predictive value of cognitive functioning on relapse and daily…
The aim of the current research project is to test the assumptions of these two models by comparing the cognitive performance of individuals with DD on several tasks (e.g., memory processing, emotion perception) with patients with trauma-related…
The main objective of this study is to investigate sex and gender differences in the prospective relationship between experienced stressors, craving and alcohol use during treatment and early recovery of AUD. The secondary objectives of this study…
The primary objective is to investigate if the stress-induced dynamics across stress systems are impaired in patients with CT-related depression compared to non-CT-related depression and healthy controls. The secondary objective is to examine how…
The aim of this project is to examine the association and interaction between environmental and genetic factors and development over time in adults with ASD. We examine if and how genetic and environmental factors might contribute to the course of…
To compare the effects of a preoperative PA program in addition to usual care versus usual care only on the change in SB from baseline (T0) to the end of the preoperative (intervention) period (T1) in patients with TAD.
The role of glutamate and GABA in cognition in subjects with chromosome 22q11.2 copy number variants
The main objective of this study is to investigate the role of glutamate and GABA in cognition in healthy subjects with 22q11.2 CNVs and healthy subjects without 22q11.2 CNVs using high-field Magnetic Resonance Spectroscopy (MRS). Additionally, we…
Primary objectives:1) Investigate the effectivity of PRIMARY on BPD related problems (especially self-harm, emotion regulation and social relationships)Secondary objectives:1) Understanding the underlying mechanisms (especially social relationships…
To examine the PVS domain, and in particular reward circuits and behaviour, in large genetically informative cohorts comprising 500 individuals (including 125 SCZ patients, 125 BP patients, 125 relatives and 125 controls) already ascertained in the…
Primary objective:To deliver an easy accessible, patient friendly and low-cost self-help intervention for the treatment of depressive symptoms in dialysis patients.Main hypothesis: An eHealth CBT intervention reduces depressive symptoms in dialysis…
The two primary objectives of this study are: 1. To increase therapeutic effectiveness of an EMDR treatment session in PTSD patients by reactivating the updated traumatic memory during post-treatment sleep using TMR; and 2. To provide a neural base…
The first aim of this research is to identify predictors of one-year treatment response after initial clinical diagnosis in a large sample of adolescent girls with AN. The results of this study could allow us to assess different treatment strategies…
The main objectives of this project are to increase our knowledge of factors playing a role in the maintenance of body image concerns in eating disorder patients. More specifically, we will examine the involvement of disgust-based avoidance of…
The aim of this project is to investigate associations between visual system functioning, ADHD, and the circadian rhythm. We will also investigate the effects on the functioning of the visual system of commonly used treatments for ADHD and related…
1. Distinguish and characterise linguistic voice-types2. Examine differential working mechanisms of voice-types3. Exploratively evaluate the role of voice-type in treatment effectiveness4. Disseminate the results to clinicians and voice-hearers
The aims of this study are:1. To describe the neuropsychiatric profiles associated with DDX3X syndrome, SETD1A syndrome, Koolen-De Vries syndrome, KBG syndrome, DYRK1A syndrome, Jansen-De Vries syndrome, Gabriele-De Vries syndrome, and Smith-Magenis…
We aim to examine the effects of an FFD on ADHD symptoms, inhibition-related brain responses and taxonomic composition and functional capacity of the gut microbiota.
The central objective is to explore the functional connectivity profiles of both STN and VS circuits during cognitive and affective tasks and compare these between OCD patients and healthy controls (HC). Secondary objectives are to assess…
To investigate the feasibility of fine-grained ambulatory cortisol signaling (total 72 hours, 20 minute intervals) in individuals with depression, PTSD and healthy controls in daily life. We will investigate whether the mean peak and trough values,…