557 results
Objective: Our general objective is to investigate the neurobiological substrates of a broader ADHD phenotype.
1. We will recruit 30 probands who meet DSM-IV inclusion criteria for a primary psychotic disorder or mood disorder with psychotic features: schizophrenia, schizoaffective disorder, delusional disorder, bipolar I disorder, psychotic depression, post…
1) To study the predicitve value of fear acquisition and extinction mechanisms on treatment outcome in anxiety disordered patients. 2) To study pathological fear acquisition and extinction in anxiety disorders: what are the differences in…
The aim of this protocol is to invite the NeuroIMAGE cohort once more for a follow-up investigation and collect phenotypical, cognitive, and MRI data. This design offers the opportunity to examine by means of longitudinal phenotypic, cognitive, and…
By achieving multiple measurements of ambulatory HRV and anxiety symptoms in one individual agoraphobia patient during a standard treatment at the University Center for Psychiatry (UCP), we will investigate how the bidirectional causal relations…
Our aim is to determine the effect of APO* on activity and volume of the hippocampus, a core structure of Alzheimer pathology, at a young age. Specifically, we aim 1) to determine the effects of APOE e4 on hippocampal activation in the young general…
This project aims to investigate the role of sleep on memory processing in PTSD. The primary aim of the study is to assess the effects of sleep architecture on emotional memory processing and neurocognitive functioning in subjects with and without…
A better understanding of the underlying mechanisms of depression in Parkinson's disease will lead to better diagnoses, treatments, and quality of life.
The objective of this study is to investigate:1) the prevalence of insomnia in patients with T2D with and without depression2) whether insomnia in patients with T2D with and without depression, is associated with increased levens of HbA1C3) whether…
Primary objectives: 1) Study EF in general and WM capacity specifically in intelligent adolescents with HFA on a neuronal and cognitive level, as well for abstract information as for social relevant information, using neuropsychological assessments…
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
The study proposes to gain more knowledge in the influence of neuropsychological characteristics, CU-traits and HPA/ANS (re)activity on treatment outcome after standardized treatment in a closed treatment setting as well as the changeability of the…
We will investigate the changes in mental performance using a validated computerize test battery of neuropsychological tests just before, three montns and one year after living kidney donation. Using visual and auditory inormation stimuli, these…
The main goal of this study is to recruit and obtain magnetic resonance images in a large sample of bipolar patients and controls from the Netherlands, in order to find brain abnormalities specific for bipolar disorder. We will also perform genetic…
• To elucidate the role of noradrenaline in the mechanisms involved in human memory consolidation• Evaluate the levels of cortisol and 3-methoxy-4-hydroxyphenylglycol in the various points of a memory consolidation window• Define pharmacological…
(1) To describe the course of non-psychotic disorders in detail, especially the emergence of chronicity and long-term dependency on professional care (2) To describe clusters of symptoms of distinct non-psychotic disorders in a way that is more…
Objective: General objective: To improve and standardize assessment of risk behaviour and its behavioural correlates in HIV patients. Specific objectives: 1) To assess sexual risk behaviour in HIV patients, 2) to assess drug related risk behaviour…
to find evidence for frontal inhibition during planning of explicit movements just as seen in patients with conversion disorders.
The project aims to gain more insight in the process of bonding between parents and prenature infants, to validate a screening instrument that can be easily adopted in maternity wards of (general) hospitals to detect parents and children at risk for…
Primary Objective:1. To investigate, within individuals, the temporal dynamics of physical activity and depressed mood.Secondary Objectives: 2. To test mechanisms in and modifiers of the relationship between physical activity and depressed mood…