60 results
Central research questions in this study are:1) To what extent are elementary school children exposed to traumatic events?2) What type events did these children experience (e.g. accidents, acts of violence, severe disease, death of a loved one)? 3)…
Cognitive processes and the development of psychopathology in children at risk for anxiety disorders
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
The objective of the proposed study is the development of a theoretical model concerning the process of working through trauma in children.
The aim of this study is to examine arousals in PTSD, and to investigate the correlation of arousals with nocturnal excretion of hormones of the HPA-axis.
Our main objective is to gain insight in the possibly causal role of belief bias in maintaining social phobia. As a subsidiary issue, we wish to disentangle the differential influences of automatic beliefs and analytic reasoning processes in…
The aim of the pilot study is to study the logistics of inviting, interviewing and examining 2000 participants from general practices in Sneek, The Netherlands. More specifically, to test the invitation procedure, the visiting schedule, the…
A prospective evaluation in a hospital setting on the frequency of post-traumatic stress disorder (PTSD) and post-traumatic stress (PTS) symptoms, following a severe post-partum hemorrhage (PPH) of 2,0 liters or more, compared to deliveries without…
The main purpose of this PhD research is to obtain more insight in the interplay between psychopathology and cultural identity among refugees from Afghanistan and Iraq and to contribute to more effective treatment plans. Information about the…
Objective: Study 1: T0 case-control observational study1) Explore if the failure to speak in specific social situations is associated with social anxiety as expressed by autonomic emotional arousal.2) To assess if the failure to speak in specific…
The main goal is to test whether individuals with a panic disorder diagnosis differ in the level of fear generalization compared to matched controls. This would be a direct replication of the seminal study by Lissek et al. (2010).
The two primary objectives of this study are: 1. To increase therapeutic effectiveness of an EMDR treatment session in PTSD patients by reactivating the updated traumatic memory during post-treatment sleep using TMR; and 2. To provide a neural base…
The central objective is to explore the functional connectivity profiles of both STN and VS circuits during cognitive and affective tasks and compare these between OCD patients and healthy controls (HC). Secondary objectives are to assess…
The general aim of this project is to better understand the mechanisms involved in safety learning, specifically in adolescents with and without clinical anxiety. First, we aim to investigate differences in vicarious and non-vicarious safety…
The primary objective of this study is to derive and externally validate a prognostic screening instrument to predict individual risk to follow an adverse PTSD symptom trajectory over the course of one year following trauma based on self-report…
The primary objective of this study is to identify the distinct roles of the peripheral and central nervous system in the subjective experience of panic.
Primary Objective: To identify reproducible neuroimaging signatures of OCDSecondary Objective: To link these neuroimaging signatures to specific cognitive functions and clinical profilesExploratory Aims: 1) To study how environmental factors may…
To explore regions of brain and brainstem activation in healthy volunteers during abdominal pain or discomfort after chemical nociceptive stimulation of the duodenum with capsaicin. In the future, we aim to perform the same study in IBS-/FD-patients…
The main objective of this study is whether EMDR is an appropriate treatment for women with PTSD after a previous birth. The resulting hypotheses are that at the two follow-up meaurements, in relation to the pretreatment-measurement 1) WITHIN the…
Main objectieve of this study is if EMDR is an effective treatment for women with FoC. Our hypotheses are that in follow-up measurement compared to the pretreatment-measurement 1) WITHIN the treatment group there will be a decrease in the severity…
We select patients that have a diagnosed anxiety disorder and are already enrolled to start an intensive exposure therapy program at Pro Persona/Overwaal. In an fMRI session their individual underlying neural mechanism (biomarker) associated with…