28 results
The main goal of this study is to validate the VR-game as a tool to provoke OCD symptoms and assess OCD symptom severity. The first objective is to investigate whether the VR-game is able to provoke OCD symptoms in OCD patients. The second objective…
To investigate the efficacy of testosterone enhanced exposure therapy for social anxiety disorder.
The study aims to answer the following research questions:1. How high/low are levels of symptomatology of depression and/or PTSD in traumatised refugee children in ASC?2. Do symptom levels decrease after a short-term trauma-focused intervention?3.…
Primary Objective: To identify dropout rates at all stages of fertility care at the fertility centres of Isala in Zwolle, Erasmus MC in Rotterdam, Reinier de Graaf group in Voorburg, Elisabeth Twee Steden in Tilburg, the St Antonius Ziekenhuis in…
The main objective of this study is to determine the role of freeze-fight-flight reactions in the development and maintenance of PTSD symptomatology.
Our primary objectives are to study in patients with OCD 1.) Whether stress facilitates a shift from goal-directed to habitual behaviour (both appetitive and avoidant); 2.) Whether stress facilitates compulsive behavior through an enhancement of…
The aim of this study is to determine the effects of propranolol on patients* crucial fear-related memories and dental trait anxiety in those undergoing surgical removal of one of their teeth or molars. The hypotheses that are tested are that…
This study addresses the following three questions:1. How do fear memories change over time?2. How is the context of fear coded in the brain?3. How can the process of excessive strengthening of fear memory be disrupted
We want to answer the following research questions:- Which of the mentioned treatment approaches is more effective for improving self-esteem?- Do both approaches have additive value (does a patient benefit more after receiving both treatments, in…
Primary Objective: Using fMRI to assess differences in brain activation during: (a) up- and down-regulation of emotional reaction to negative and positive pictures vs neutral pictures; and (b) working memory at low and high load with emotional…
Primary Objective is to determine whether (A) patients with dystonia(plus) syndromes exhibit more psychiatric symptoms compared to a healthy control group and (B) whether dystonia patients show an altered serotonin metabolism (serotonin transporter…
The current proposal aims at investigating the effect of a multidisciplinary non-verbal intervention on the awareness and modulation of WRA to improve self-efficacy, mobility, mood, and quality of life as compared to usual care.
The current study aims at investigating whether individual mindfulness-based cogntiive therapy (MBCT) online and MBCT offered face-to-face in groups are superior to a waiting list-control group in terms of improvement of depression and anxiety,…
Investigation of the effect of interpretive bias modification on anxiety levels in dental phobia. If CBM-I indeed has positive effects in the treatment of dental phobia, it could be integrated in the treatment-as-usual as an additional intervention…
This study will examine the efficacy of this Virtual Reality Exposure Therapy (VRET) in a CSA and war related trauma sample by comparing it with treatment as usual (TAU). It will also attempt to develop protocols to implement this new technology…
The aim is to determine on the basis of the results of this study whether there is measurable effect on the ability to drive after long term use of ICADTS class III drugs. To achieve this goal drugs will be tested out of the groups most commonly…
Objective: The main objective is to evaluate the effectiveness of the POPP-treatment program in reduction of severity of post-traumatic stress symptoms for sexually abused preschoolers. Secondary objectives are to evaluate the effectiveness of the…
The first objective is to assess the effect of age and anxiety disorder on use and effectiveness of emotion regulation strategies in circumscribed vs. complex daily life situations. The second objective is to assess the effect of treatment of…
The objective of our study is to examine the effectiveness of a cognitive behavioural therapy based intervention compared to an information leaflet on anxiety symptoms after one month, in patients presenting at the emergency unit with non-cardiac…
The primary aim of the proposed RCT is to evaluate whether younger and older adults with mild to moderately severe anxiety symptoms gain similar treatment benefits from an online-based psychological treatment (Acceptance and Commitment Therapy: ACT…