65 results
The objective of the study is to identify biomarkers that associate to brain (physiological) status or mental (functional) health status and their interaction. More specific, our first aim is to determine the association between neuroinflammatory…
To explore the relation between (changes in) cerebrovascular function and the change in cognitive function in older adults with and without MCI across follow-up.
To investigate the relationship between subjective and objective ADHD and subjective mood symptoms and the menstrual phase in women with and without ADHD.
Primary ObjectiveOur primary objective is to investigate the effect of SVD-progression on the long-term clinical outcome. Secondary Objectives- To identify causes and risk factors related to an unfavourable clinical outcome over time- To identify…
The main objective is to pinpoint the biological pathways that set long-term risk of CVD and NDI when epigenetically disturbed during fetal development by (1) establishing a longitudinal cohort of MC twins, (2) defining epigenetic alterations…
The role of glutamate and GABA in cognition in subjects with chromosome 22q11.2 copy number variants
The main objective of this study is to investigate the role of glutamate and GABA in cognition in healthy subjects with 22q11.2 CNVs and healthy subjects without 22q11.2 CNVs using high-field Magnetic Resonance Spectroscopy (MRS). Additionally, we…
The aim of this pilot study is to explore the structure and function of brain regions associated with the pain matrix in Breast Implant Illness (BII). This pilot study will be the foundation for grant application for future research.
The aim of this project is to investigate associations between visual system functioning, ADHD, and the circadian rhythm. We will also investigate the effects on the functioning of the visual system of commonly used treatments for ADHD and related…
The main objective is to assess long-term neurodevelopmental, cardiovascular, pulmonary, and growth outcomes in a cohort of MC twins with sFGR and to compare outcomes within sFGR twin pairs.
To determine whether reactive gliosis persists >3 years after SAH and whether this response relates to cognitive impairment after SAH.
Primary objective: Development of a normal tissue complication probability (NTCP) model for hypothalamic dysfunction (for severe hypothalamic dysfunction, named hypothalamic syndrome) in childhood brain tumor survivors, incorporating cranial…
The main objective of CRUCIAL-VCI is to determine a surrogate MRI marker for microvascular density in patients with VCI due to cSVD, and to relate this to disease severity expressed as macrostructural brain damage and cognitive function. The…
We aim to assess the association between variability and irregularity in heart rate (as caused by permanent atrial fibrillation), and cognitive function. In addition, variability and irregularity of the peripheral blood pressure will be correlated…
To investigate plasticity in the visual cortex in NF1 patients, we will compare the VEPs evoked by checkerboard reversals at baseline and after a modulation block at T1, T2 and T3 of NF1 patients with those of controls.
Primary objective: To test in patients with ESRD whether a longer HD session (8 hours) compared with CHD limits the decline in cerebral blood flow.Secondary objectives: 1) to investigate whether a longer dialysis session is associated with superior…
Primary Objective: - To investigate whether or not persistent complaints and poor outcome after mTBI be explained by an interaction between physiological and psychological factors.Secondary Objective(s): - To identify specific patterns of brain…
The objective of this study is to elucidate unique and shared impairments across a broad range of social cognition tasks (at the behavioral, neuropsychological, and neurophysiological level by means of EEG recordings) related to subdimensions of…
(1) To investigate the relationship between estradiol level and ADHD and mood symptoms within the menstrual cycle in women with ADHD. (2) To investigate if this relationship is comparable between women with and without ADHD.
We will study the cerebral glucose metabolism before, during and after surgery by sampling the cerebrospinal fluid (CSF) via the spinal catheter in patients undergoing thoracic surgery. Changes in cerebral glucose metabolism and activation of the…
To investigate the role of the dopaminergic system in reward discounting and reward anticipation in ADHD and comorbid disorders. The study investigates the following question: Do patients with ADHD without comorbidity differ from those with ADHD and…