226 results
Here we propose that in order to identify causal mechanisms that explain AD/HD-related heterogeneity, an integrative approach is needed. Therefore, in this project we will study the interaction between motivation and executive function in AD/HD and…
- The primary objective of this proposal is to assess the intraindividual reliability of PAS TMS, Theta-burst rTMS and ppTMS indices as measures of neural plasticity and cortical inhibition, by performing test-retest measurements separated by a…
Our interest is to gain a better understanding about cognitive complaints, mood and fatigue in relation to cognitive deficit in adults 30 to 60 years of age after a first cardiac event.
Objective: The primary objective of this study is to investigate whether pain experience decreases or increases when cognitive functions decline in patients with Parkinson's disease. Furthermore will be investigated whether this is influenced…
The purpose of the study is to investigate how quickly and to what extent RO5285119 is absorbed from the gut and then eliminated from the body (this is called pharmacokinetics).It will also be investigated to what extent RO5285119 is tolerated.
The main objective is to explore the effects of mulimodal treatment upon empathic skills in forensic male adolescents with ADHD, with or without DBD. A secundair objective is to explore the effects of multimodal treatment upon antisocial behavior.
The next questions will be addressed in the present study: 1. Do moderately preterm infants differ in development and attention and concentration capacities from a term and very preterm infants during the first years of life? 2. Do attention and…
Our primary objective is to evaluate the effectiveness of mindfulness training in improving self-control of youth with ADHD. As secondary objectives, we aim to quantify the effectiveness in reducing ADHD symptoms, reducing comorbid (e.g. ASD)…
To identify brain determinants (moderators) and mechanisms (mediators) of ADHD persistence into adulthood by studying fine-grained neuroanatomy and connectivity in a longitudinal study of genetically stratified patients across the full spectrum of…
The primary objective of this study is to investigate in a randomized controlled trial (RCT) if AquaSnap can improve cognitive functioning in patients with DSM-IV-TR diagnosis of schizophrenia/schizoaffective disorder, OCD or MDD who have cognitive…
To conduct a pilot study on the relationship between measured sensitivity to reward and the effectiveness of a routine cognitive-behavioral intervention in ADHD. To pilot relevant measurements and generate hypotheses for a larger study in the future…
To objective of this protocol is threefold.1. To investigate transdiagnostic cognitive deficits across a diversity of different psychiatric disorders.2. To link cognitive deficits with symptom-dimensions, EEG, cortisol, genetic and other blood…
The objective of this experiment is to establish the effects of tyrosine suppletion on cognitive symptoms seen in ADHD. Cognition will be assessed, while simultaneously recording brain activity.
Posner spatial cueing task will be used to investigate electrophysiological differences in brain oscillatory lateralization during attentional shifts in children with and without ADHD. We hypothesize that the observed difference in the ability to…
We aim to validate MRS with a cholinergic challenge as method to investigate muscarinic M1 receptor functioning. To investigate the relationship between the response to a muscarinic receptor antagonist with biperiden phMRI and [123I]IDEX SPECT…
Previous studies have suggested an association between FD and cognitive impairment but these were flawed either by lack of power, used variable assessment of cognitive functioning and/or merged results of different phenotypes and sexes. It is of…
The comparison of the effects (and cost effectiveness) of mindfulness training for the child + Mindful Parenting for the parents versus medication (Methylphenidate) in a randomized controlled trial (RCT) in children with ADHD, aged 9-18.
The proposed study aims to bring neuroimaging and genetics closer to the child/adolescent psychiatric clinic by developing automated classifiers, and obtain associated multimodal biomarker profiles. Such biomarkers are prospected to, aid in clinical…
Primary: To compare the efficacy of aripiprazole with placebo in the suppression of tics in children and adolescents (7-17 years) with a diagnosis of Tourette*s Disorder. The primary efficacy measure is change from Baseline to endpoint (Week 8) on…
The aim of this study is to explore the prevalence of HAND in people living with HIV.