20 results
The above anounced studies suggest that some abnormalities in the Wnt pathway can be expected to affect development and function of the brain, potentially leading to recognizable behavioural phenotypes. Given the key role of APC in the Wnt pathway,…
The next questions will be addressed in the present study: 1. Do moderately preterm infants differ in development and attention and concentration capacities from a term and very preterm infants during the first years of life? 2. Do attention and…
The primary objective of this study is to evaluate neurophysiologic changes of the pain centres of the brain (the differences in particular in the thalamus, primary and secondary somatosensory cortex, insula, anterior cingulate cortex and the motor…
The aim of this study is to explore the prevalence of HAND in people living with HIV.
Primary :to evaluate the safety and tolerability of EVP-0962 after single and multiple ascending dose administrations in healthy subjectsSecondary :to determine the pharmacokinetic profile of single and multiple oral doses of EVP-0962 and to assess…
To investigate whether adult patients with ADHD without and with methylphenidate treatment show impairments in affective and complex social cognition tasks compared to an (already existing) healthy control group.
The aim of this study is to test the feasibility, reliability and validity of a Dutch version of the Penn Computerized NeuroPsychological testing system (CNP). It is tested wether our translated version is feasible for use in the Dutch population at…
This study focusses on the added value of neuropsychological and psychophysiological factors in predicting treatment response of delinquents in the CoVa training. The aim is to figure out in what way neuropsychological and psychophysiological…
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Our unique project is based on an ongoing European prenatal stress research focusing on the effect of prenatal stress on early sensory-cognitive development. We capitalize on the methodologically sound maternal and infant physiological measures…
The aim of the study is to explore the prevalence of HAND in people living with hiv.
The main objective is to investigate the role of MRs in memory acquisition and recall during stress and non-stress conditions. Specifically, we are interested in two domains of memory, spatial and fear memory. Secondary objectives are to determine…
Investigate the hypothesis that children with ADHD have difficulty with the allocation of visio-spatial attention related to an inability to control posterior alpha. A paradigm will be used in which the aim is to address covert attention as similar…
The objective of the study is to investigate effects of training on insulin resistance (IR), chronic heart failure (CHF) and cognition of resthome residents.
To study whether the administration of oxytocin leads to stronger empathic responses on 3 different empathy-related tasks compared to a placebo.
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
The objective of this study is to investigate the acceptance, feasibility and efficacy of cognitive behavioral therapy in reducing ADHD symptoms for adult patients with ADHD and SUD. We will also investigate how substance use and craving are…
Primary: The primary objective of this study is to evaluate the long-term safety of SPD489 administered as adaily morning dose (30, 50, and 70mg) in the treatment of children and adolescents (6-17 years of ageinclusive at the time of consent in this…
Examine how unexpected reward and unexpected punishment affect working memory, that is, the ability to maintain information across time, update task-relevant information and ignore task-irrelevant information.Determine the extent to which…
In our recent studies we found indications of the existence of particular cognitive deficits as well as memory impairments following different regiments of cytostatic agents. Together with the indications form our animal studies of a potential…