77 results
To examine the (cost)effectiveness of mindfulness versus treatment as usual (TAU) in adults with Attention Deficit Hyperactivity Disorder (ADHD).
The comparison of the effects (and cost effectiveness) of mindfulness training for the child + Mindful Parenting for the parents versus medication (Methylphenidate) in a randomized controlled trial (RCT) in children with ADHD, aged 9-18.
The primary objective of this study is to investigate in a randomized controlled trial (RCT) if AquaSnap can improve cognitive functioning in patients with DSM-IV-TR diagnosis of schizophrenia/schizoaffective disorder, OCD or MDD who have cognitive…
Provide proof-of-concept for the hypothesis that guanfacine diminishes cognitive side-effects in ER+ BC patients treated with adjuvant hormonal therapy. Secondary, provide data for power calculations in later studies.
Our primary objective is to evaluate the effectiveness of mindfulness training in improving self-control of youth with ADHD. As secondary objectives, we aim to quantify the effectiveness in reducing ADHD symptoms, reducing comorbid (e.g. ASD)…
To investigate the efficacy of a less intensive but more prolonged Cogmed © RM WMT (including active personalized coaching and feedback) in reducing behavioral symptoms and improving neurocognitive functioning and academic achievements in children…
The objective of this experiment is to establish the effects of tyrosine suppletion on cognitive symptoms seen in ADHD. Cognition will be assessed, while simultaneously recording brain activity.
The purpose of the study is to investigate how quickly and to what extent RO5285119 is absorbed from the gut and then eliminated from the body (this is called pharmacokinetics).It will also be investigated to what extent RO5285119 is tolerated.
The main objective is to explore the effects of mulimodal treatment upon empathic skills in forensic male adolescents with ADHD, with or without DBD. A secundair objective is to explore the effects of multimodal treatment upon antisocial behavior.
• To evaluate short-term (directly after training) and long-term (12 months) effects of cognitive rehabilitation on (working)memory, attention, concentration, and quality of life; measured by neuropsychological assessments, and reports by parents…
Primary Objective:The primary objective in the current trial is to use graph theory to examine how the organization of the functional brain network may be altered by the administration of methylphenidate. The main question we intend to answer in…
The main goal of the study is to measure the effectiveness of the Patient and Partner Education program 4 all (PPEP4ALL) in patients with hypoxic brain injury and/or their spouse/caregiver.
Primary objectives:To determine the exposure-response relationship of EVP-6124 over a range of plasma concentrations in a scopolamine-induced cognitive deficit model in healthy elderly subjects.Secundary objectives:To determine the exposure-response…
We aim to examine, in the impaired older population, whether a treatment using methylphenidate, a DA re-uptake inhibitor that enhances DA, improves attention and memory.
Primary :to evaluate the safety and tolerability of EVP-0962 after single and multiple ascending dose administrations in healthy subjectsSecondary :to determine the pharmacokinetic profile of single and multiple oral doses of EVP-0962 and to assess…
The primary aim of our study will be to investigate the effectiveness of PCIT in comparison with methylphenidate in children with ADHD and disruptive behavior problems aged 2;6 till 6 years who have not responded sufficiently to previously offered…
To study the effects of Mindfulness training in adults with ADHD on ADHD symptoms and comorbidity with affective and anxiety symptoms. Also, the feasibility of Mindfulness training will be evaluated in this specific patientgroup and the effect on…
zie boven
- to evaluate the safety and tolerability of a single oral dose of SCH 900229 administered to healthy adult volunteers- to characterize the pharmacokinetic (PK) profile of SCH 900229 in plasma of healthy adult volunteers after a single oral dose- to…
The primary objective of this study is to provide access to SPD503 following participation in SPD503-315 or SPD503-316. The primary outcome of this study is to evaluate the long-term safety of SPD503. The evaluation of safety will be based on the…