77 results
Primary Objective: To determine the effectiveness of methylphenidate in reduction of ADHD symptomatology, operationalized by personalized goals that are important to the patient and its environment, in individuals with late-diagnosed PKU. Secondary…
Primary objective: To investigate the feasibility of a program for functional remediation for patients with BD-I or recurrent MDD, through • Evaluation of user experiences with the program. • Evaluation of drop-out and reasons for drop-out. •…
The aim of the current study is to develop an internet-based cognitive intervention programme for occupationally active cancer survivors confronted with cognitive problems and to evaluate the (cost-)effectiveness of this programme.
To investigate the feasibility of a combination therapy (consisting of individualized rTMS and cognitive strategy training) and study measurements in patients with a primary brain tumor during stable disease. The study is considered feasible when 80…
The primary objective is to compare the pharmacological profile of the magistral form of dexamphetamine sulphate to the pharmacological profile of the brand-name form of dexamphetamine (Tentin©) in adult patients diagnosed with attention deficit…
The main objective of this study is to compare the acute effects of methylphenidate on behavioral and cognitive functioning in 6 to 12 year old treatment naïve children compared to the effects after nine months of treatment with methylphenidate in…
Primary objective is assessment of the pharmacokinetic profile of MPD in pregnancy. Secondary objectives are the safety and efficacy of any use of MPD during pregnancy.
Goal of the study is to find out if cognitive remediation focused on executive functioning for patients with bipolar disorder improves (1) functioning on personal goals in everyday life? And (2) improves general wellbeing?Hypotheses:Cognitive…
Primary objective of the study: 1. To report on the long-term effect modification by age of MPH treatment on the outgrowth of the DA system using state-of-the-art Magnetic Resonance Imaging (MRI) techniquesSecondary objectives:1. To report on the…
Primary Objective: To assess the effectiveness of a personalized executive functioning training program for 4-6 year old children with severe CHD.Secondary objectives: - To relate training effectiveness to disease and treatment characteristics and…
The primary objective of this study is to determine whether self-reported spatial navigation impairment complaints in acquired brain injury patients are reduced as a result of engaging in a behavioural navigation rehabilitation training. The…
We will examine the cognitive performance of healthy young participants at different time points after a single administration of biperiden. The behavioural outcomes and electrophysiological correlates will be linked with the serum levels of…
Investigating the efficacy and feasibility of working memory training in COPD patients on cognitive performance, cognitive stress susceptibility and perception, self-control / impulse control, and adherence to physical activity and dietary…
The objective of this proposal is to determine the effect of Lamotrigine on cognitive functioning and neurophysiology in adolescents with NF1.
The objective of this pilotstudy is primarily to assess a cost-efficient, easy accessible training of cognitive functions on its feasibility and initial effect in patients with cognitive dysfunction in PD, MS of patients treated with ECT. Using this…
Primary objective:investigating whether in a large, representative sample of premature born children (gestational age * 30 weeks and/or birth weight * 1000 gram) with attentional problems in the age of 8 - 12, executing the BrainGame Brian training…
The purpose of the study is to investigate how quickly and to what extent balovaptan is absorbed and eliminated from the body when it is administered to healthy volunteers. The pharmacokinetics of balovaptan given by mouth (oral) will be compared…