224 results
Primary objectives:To determine the exposure-response relationship of EVP-6124 over a range of plasma concentrations in a scopolamine-induced cognitive deficit model in healthy elderly subjects.Secundary objectives:To determine the exposure-response…
We aim to examine, in the impaired older population, whether a treatment using methylphenidate, a DA re-uptake inhibitor that enhances DA, improves attention and memory.
To study neuronal and ophthalmological characteristics of a newly detected clinical entity called slow vision which hampers visual perception and attention of the affected patients.
The objective is to assess the gait characteristics of adults with intellectual disabilities by other causes than Down syndrome, and without diagnosed neurological conditions (Parkinson's disease, cerebrovascular accident, dementia, and…
First objective: this study will compare executive functioning of normal-weight participants (controls) to overweight/obese participants, in relation to food related stimuli and non food-related stimuli.Second objective: this study will examine if…
This study aims to investigate the effect of switching from Atripla® to Eviplera® on neurocognitive performances (neurocognitive testing) and imaging (functional MRI scanning) in virologically suppressed HIV-infected patients and stable on atripla.
Developing a short (+/- 30-40 minutes) computerised test which can measure a large amount of cognitive characteristics of ADHD, and as such can identify a profile of cognitive strengths and weaknesses. The identification of such a subtype serves:•…
The aim of this study is to explore the prevalence of HAND in people living with HIV.
Primary :to evaluate the safety and tolerability of EVP-0962 after single and multiple ascending dose administrations in healthy subjectsSecondary :to determine the pharmacokinetic profile of single and multiple oral doses of EVP-0962 and to assess…
The primary aim of our study will be to investigate the effectiveness of PCIT in comparison with methylphenidate in children with ADHD and disruptive behavior problems aged 2;6 till 6 years who have not responded sufficiently to previously offered…
To investigate whether adult patients with ADHD without and with methylphenidate treatment show impairments in affective and complex social cognition tasks compared to an (already existing) healthy control group.
The aim of this study is to test the feasibility, reliability and validity of a Dutch version of the Penn Computerized NeuroPsychological testing system (CNP). It is tested wether our translated version is feasible for use in the Dutch population at…
Research into the effects of memory training on behavior and cognitive performance of ADHD children.
Studying and comparing the short and long-term effects of two different memory trainings on the behavior and cognitive performance of children with ADHD within a controled design. Training excersizes are dereived from a published training from…
To study the effects of Mindfulness training in adults with ADHD on ADHD symptoms and comorbidity with affective and anxiety symptoms. Also, the feasibility of Mindfulness training will be evaluated in this specific patientgroup and the effect on…
This study focusses on the added value of neuropsychological and psychophysiological factors in predicting treatment response of delinquents in the CoVa training. The aim is to figure out in what way neuropsychological and psychophysiological…
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Our unique project is based on an ongoing European prenatal stress research focusing on the effect of prenatal stress on early sensory-cognitive development. We capitalize on the methodologically sound maternal and infant physiological measures…
1. To determine the level of cognitive, emotional and cardiorespiratory impairment, daily functioning, participation in society, quality of life and partner strain up to one year after the survival of a cardiac arrest.2. To determine prognostic…
The aim of the study is to explore the prevalence of HAND in people living with hiv.
The main objective is to investigate the role of MRs in memory acquisition and recall during stress and non-stress conditions. Specifically, we are interested in two domains of memory, spatial and fear memory. Secondary objectives are to determine…