224 results
The aim of this study is to test the feasibility of a GXTT, combined with a SET in adults with ID, through completion rate of the GXTT and the SET, the subjective experience of the participants and determining if the VO2peak of the SET is likely to…
The study objective is primarily to measure the effect of an online cognitive training in patients with mild cognitive complaints in PD. An online training, specifically altered for PD patients (BrainGymmer) will be compared with an active online…
The objective of the study is to identify biomarkers that associate to brain (physiological) status or mental (functional) health status and their interaction. More specific, our first aim is to determine the association between neuroinflammatory…
This study aims to investigate whether mijnfittebrein.nl has a positive effect on cognition in cancer patients after chemotherapy treatment, compared to treatment as usual.
The purpose of this study is to investigate how safe modafinil is and how well it is tolerated when it is administered in combination with aniracetam to generally healthy elderly volunteers with subjective cognitive decline. Modafinil and aniracetam…
To explore the relation between (changes in) cerebrovascular function and the change in cognitive function in older adults with and without MCI across follow-up.
To investigate the relationship between subjective and objective ADHD and subjective mood symptoms and the menstrual phase in women with and without ADHD.
Primary ObjectiveOur primary objective is to investigate the effect of SVD-progression on the long-term clinical outcome. Secondary Objectives- To identify causes and risk factors related to an unfavourable clinical outcome over time- To identify…
The main objective is to pinpoint the biological pathways that set long-term risk of CVD and NDI when epigenetically disturbed during fetal development by (1) establishing a longitudinal cohort of MC twins, (2) defining epigenetic alterations…
To investigate the efficacy of targeted nutrient supplementation on daily physical activity level as well as generic health status in patients with moderate to very severe COPD. Additionally, we aim to disentangle the relative effect of targeted…
Primary Objective: To determine the effectiveness of methylphenidate in reduction of ADHD symptomatology, operationalized by personalized goals that are important to the patient and its environment, in individuals with late-diagnosed PKU. Secondary…
Primary objective: To investigate the feasibility of a program for functional remediation for patients with BD-I or recurrent MDD, through • Evaluation of user experiences with the program. • Evaluation of drop-out and reasons for drop-out. •…
The role of glutamate and GABA in cognition in subjects with chromosome 22q11.2 copy number variants
The main objective of this study is to investigate the role of glutamate and GABA in cognition in healthy subjects with 22q11.2 CNVs and healthy subjects without 22q11.2 CNVs using high-field Magnetic Resonance Spectroscopy (MRS). Additionally, we…
The aim of this pilot study is to explore the structure and function of brain regions associated with the pain matrix in Breast Implant Illness (BII). This pilot study will be the foundation for grant application for future research.
The aim of this project is to investigate associations between visual system functioning, ADHD, and the circadian rhythm. We will also investigate the effects on the functioning of the visual system of commonly used treatments for ADHD and related…
The primary objectives are to investigate in older adults the effect of 16-week wild blueberry consumption on (regional) vascular function and insulin-sensitivity in the brain, while we will also focus on changes in cognitive performance as assessed…
The main objective is to assess long-term neurodevelopmental, cardiovascular, pulmonary, and growth outcomes in a cohort of MC twins with sFGR and to compare outcomes within sFGR twin pairs.
To determine whether reactive gliosis persists >3 years after SAH and whether this response relates to cognitive impairment after SAH.
The aim of the current study is to develop an internet-based cognitive intervention programme for occupationally active cancer survivors confronted with cognitive problems and to evaluate the (cost-)effectiveness of this programme.
Primary objective: Development of a normal tissue complication probability (NTCP) model for hypothalamic dysfunction (for severe hypothalamic dysfunction, named hypothalamic syndrome) in childhood brain tumor survivors, incorporating cranial…