61 results
EDGI aims to enhance the understanding of the underlying biology and genetic architecture of the different eating disorders. Therefore GWA analyses (both within and cross disorder analyses) will be performed in the EDGI samples combined with the PGC…
The primary objective of the current study is to investigate whether self-disgust is heightened in patients with AN. If this indeed is the case, this would provide important leads to improve existing treatment options for AN.
The primary question in this study is: what is the weight development for adolescents with an eating disorder during FBT? The secondary objectives are about the course of eating disorder symptomatology, as well as anxiety and mood complaints. And in…
Objective: In this study we propose elucidating the pharmacokinetics of olanzapine in AN patients, to optimize the dosing strategy, to the extent of increasing the efficacy and reducing the risk of side effects. To this end, we will assess the…
This study evaluates the efficacy and applicability of schema therapy for anorexia nervosa.
The current pilot study aims to investigate whether diversity and composition of the intestinal microbiota are different in patients with enduring anorexia nervosa compared to matched controls. Furthermore, this study aims to explore whether…
The current study aims to investigate whether vitamin and mineral status is associated with executive functioning in patients with an eating disorder. Key objectives: 1.To investigate the micronutrient status in patients with an eating disorder…
Primary Objective: To assess AET*s effectiveness concerning eating disorder symptoms, autonomy-connectedness (primary outcome measures), general psychopathology, self-esteem and quality of life (secondary outcome measures). Secondary Objective(s):…
This study will clarify to what extent adding the EMDR protocol in the treatment of ED will lead to a change in self-reported PTSD symptoms, injured self-image, clinical perfectionism and negative body perception as underlying transdiagnostic…
To determine DBCI acceptability by examining how participants respond to the intervention, their views, perceptions, thoughts, feelings, benefits and barriers. To determine DBCI acceptability by examining Elipse providers views, perceptions,…
This proposed pilot is part of a bigger project led by 5M ICT. In the bigger project, 5M ICT will apply a deep learning (DL) method for food recognition on images taken by the user before and after eating, which enables accurate tracking of…
In this study a performance-based psychomotor measuring instrument of aggression regulation is developed for clinical and research purposes and tested on its psychometric quality. This instrument is called the *Method of Stamp Strike Shout* (MSSS)…
Objective: The primary objective of this study is to investigate interoceptive abilities in adolescents with AN. To capture the multidimensional perspective, interoceptive abilities will be studied on an accuracy, sensibility and awareness level.…
The primary objective of this study is investigating whether AN patients and healthy controls differ in how they estimate the size of their shoulders, waist, and hips before and after induction of the OBI. We will specifically investigate whether…
GSH CBT-E is an internet-based guided self-help intervention. Objective of this study is to investigate the effectiveness of GSH CBT-E in comparison with a waiting list condition on frequency of binge eating (BE). Secondary objective is to measure…
To study the differences in MI between short-term ill adolescents with AN (< illness duration 1 year) and patients who started their illness in adolescence and have been ill for at least 5 years consecutively and with healthy controls. A…
The primary objective of the study is to examine the effects of group SFT for an out-patient ED population, as assessed by change in both ED pathology as in core self-beliefs. Hypotheses:1. There will be a decrease in dysfunctional core self-beliefs…
Deep Brain Stimulation in Patients with Chronic Treatment Refractory Anorexia Nervosa: a Pilot Study
The aims of this research project are:1) to establish the efficacy and feasibility of DBS as a last resort treatment in patients with chronic, treatment refractory AN. 2) to associate the efficacy and functional effects of DBS in patients with…
Primary Objective: a) piloting the intervention- to identify whether DBI is feasible and acceptable (tolerability, appropriateness, usefulness) being studied from both the perspective of study participants, the research team and clinicians, and…
Primary objective: To investigate the effect of fecal transplantation (harvest from donors with a normal BMI, 22-25 kg/m2) in patients with anorexia nervosa between baseline and after 6 and 12 weeks. Our primary endpoint is the change in the…