23 results
Primary ObjectiveEstimate the proportion of subjects fulfilling criteria for symptomatic remission (as defined by Andreasen et al.)* following a transition to 12 months* treatment with flexible-dose PP3M in subjects with schizophrenia previously…
To develop a 360o video VR relaxation program (VRelax) for reducing impact of stress in patients with depressive, anxiety and psychotic disorders. Feasibility, user-friendliness and immediate effects on subjective and objective stress reactivity…
The primary aim of this study is threefold. The first objective is to determine whether the SCL and the frequency of non-specific skin conductance response (nsSCRs) measured by the Philips GTEP Emography Bracelet are accurate measures of sympathetic…
The aim of this study is to investigate the feasibility and efficacy of a combined treatment for PTSD and problematic alcohol use (PAU) in a Dutch sample of older patients with PTSD and PAU. Expertise from Brijder addiction care will be shared with…
The aim of the present study is to investigate whether EMDR is an effective method to treat low self-esteem and if this is more effective than CBT. Hypothesis:1. Participants will improve on measures of self-esteem, psychological symptoms and social…
The objective of the proposed research is to address the effectiveness of neurofeedback and exercise as non-pharmacological treatments for ADHD. The effects of neurofeedback and exercise will be assessed on three domains: behaviour, neurocognition,…
Main: to examine the comparative and combined effects of aggression replacement training (ART) and Risperidone on aggressive behaviours among adolescents with aggression problems ages 14-21 across clinical and non clinical settingsSecondary: to…
Is there an increase in markers of trombogenese (platelet activation, d-dimeer, von willebrandfactor, OPG) in elderly users of antipsychotics six to ten days after the start in comparison to the same markers before start of the antipsychotic…
The main objective of the study is to investigate whether an 8 week MFT for children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD) as well as an 8 week MPT for parents, would be effective in…
A randomized multicentre trial is proposed. The aim of this study is to find answers to the following questions; 1) what is, compared to care as usual, the effect of MBT with respect to symptoms, level of functioning and well being, (mental) health…
Further development and validation of two tools to measure patient progress in the psychiatric health care; the behavioral health status (BHS) questionnaire and the Heart Rate Variability (HRV) measures.
The study aims at finding answers for the following questions:-What changes develop in the perception of patients concerning their daily functioning (inclusing the impact of mental disorders) and how are these changes related to the photo-story they…
- research the efficacy of a new group cbt: 'to control thoughts and feelings'- to indicate whether a randomized controlled study is advisable
The current pilot study will explore 1) whether the effect of blended parent training is noninferior to the effect of face to face parent training, 2) whether therapist time can be reduced by offering the intervention partially online, 3) whether…
The aim is to study the effectivity of a brief, intensive, outpatient group treatment (ERP) for youths with chronic tic disorders/Tourette Syndrome (TS), to improve treatment outcome, daily functioning/quality of life and treatment satisfaction. If…
It is investigated whether EMDR is effective in reducing post-traumatic stress reactions in young children (1.5 to 8 years), reducing co-morbid emotional and behavioral problems and whether the results will be maintained 3 months after treatment. In…
The overall objective of this study is to use standard clinical measures to explore the safety and effects of open-label manualized MDMA-assisted psychotherapy with a flexible dose of MDMA in participants with severe PTSD, and to serve as an…
The primary objective of the study is to evaluate the long term safety and tolerability of troriluzole as adjunctive therapy in subjects with OCD who have had an inadequate response to standard of care (SOC) treatment for OCD and as defined in the…
Primary Objective: The objectives of this study are to adapt the VRAPT protocol and manuals for people with MBID, and to test the feasibility of VRAPT-ID in a sample of people with MBID and aggressive behavior. Feasibility will be assessed by…
The aim of the proposed research is to test the effect and evaluate the PMT module Safe and Strong, a psychomotor intervention targeting the consequences of sexual abuse in people with MID-BIF and improving the body experience and psychological…