35 results
The primary objective of the proposed study is to examine the neural substrate of cognitive and social-emotional apathy in patients with schizophrenia. Secondary, we intend to explore the concentration of brain metabolites and structural differences…
The proposed experimental pilot study focuses on harm reduction in a specific subpopulation, i.e. in patients with schizophrenia (long-term psychotic disorder) with a suboptimal response to the currently available interventions, smoking a lot of…
The main objective of the study is to gain insight into the cost-effectiveness of BPR compared to care as usual (CAU) for patients withSMI who have a wish for change in their societal participation. Research questions:1. Is BPR (cost-)effective…
1.Social CognitiveA.Do schizophrenia patients, compared to unaffected controls, show impaired social cognition (perceiving, understanding, intentions and emotions of others), especially when it comes to self-other distinction processes (…
The objective of the current study is to obtain normative data of healthy individuals on brain measures, cognition and blood markers. In addition, we acquire information on childhood trauma, metabolic and immunological parameters in a cohort of…
The aim of this project is to elucidate the mechanisms underlying one of the most incapacitating psychiatric disorders, psychosis. Despite antipsychotic treatment, up to a third of patients with psychotic illness continue to experience significant…
The first goal of this research is to translate the IMI-SR into a valid and reliable Dutch version of this questionnaire (N-IMI-SR). The second objective is to assess whether there is an association between IM and cognition in schizophrenia.
The goal of this pilot study is to (i) investigate which measurements are suitable best for the evaluation of (cost) effectiveness, (ii) investigate whether CAT can be given as a nursing intervention (feasability).
The primary objective of this study is to evaluate in a randomized controlled clinical trial the clinical effectiveness of TAT on the proportion of medication non-adherent patients over 24 months, in schizophrenia outpatients who have poor…
The aim of this study is to demonstrate the influence of a serious diagnosis like schizophrenia has happiness in relation to daily activities.
This study aims to investigate the effectiveness of the CARe methodology in terms of rehabilitation, participation, empowerment, hope and confidence, fullfilled needs for care and quality of life. The central research question is: *Does the support…
The primary objective of this study is to examine whether web-based Wegweis tool can support processes of shared decision making in ROM evaluation and treatment planning regarding people with psychotic disorders.
The aim of the current study is to investigate which gene-abnormalities can be related to brain deficits and symptoms associated with schizophrenia.
- To investigate whether olanzapine influences the (psychomimetic) effects of THC, in particular on the Positive and Negative Syndrome Scale (PANSS) - To further explore the pharmacologic basis of the THC model - To investigate the effects of…
The aim of the proposed research is to test the hypothesis that lack of insight in psychosis is associated with reduced activation of brain circuits subserving self-evaluation and emotion regulation and that this relationship is also dependent on…
To investigate whether patients with schizophrenia show reliable and consistent brain activations as measured with fMRI to two different stimulation paradigms and wether they differ in terms of the patterns or the intensity of activation as compared…
To assess the effects of home automation on client satisfaction with services, functioning, fulfillment of needs for care, quality of life, and service contacts.
Primary objective: the primary goal is to investigate the effect of audiobooks on quality of life, general psychopathology, the experienced power of the voices and the burden of the voices.Secondary objective: the second goal is to determine whether…
The objective of the study is to investigate whether the application of the multidisciplinary guidelines for the treatment of schizophrenia leads to a better course of schizophrenia and related disorders.
The objective of this study is threefold. First, to investigate neural correlates of cognitive-emotional processing in an ARMS sample, i.e. help-seeking young people with an at-risk mental state (this will be addressed in the base-line measurement…