55 results
To investigate the impact of the multispecies probiotic product Ecologic*Barrier on neurocognitive measures of emotion and executive functioning.
The primary objectives are (1) to investigate the feasibility of online courses targeting nutrition and food-related behaviour and (2) to investigate whether the feasibility of the online courses is related to depressive symptoms. The secondary…
Objective: We would like to differentiate *normative mood swings*. in adolescence from early signs of depression. A comparison between low-risk adolescents and an at risk and a clinically referred sample is needed to detect an unrecognized subsample…
This study aims at the questions about anterograde amnesia. How often does it occur in patients being treated with bilateral ECT for a depressive disorder, how does anterograde amnesia develop during the treatment course and how does it subside…
Primary Objective: * To determine the effects of pharmacogenetic screening for CYP2D6 on the time to reach adequate serum drug levels according to the guidelines.Secondary Objective(s): * To determine the effects of pharmacogenetic screening for…
The objective of this study is threefold:1) compare the effectiveness and cost-effectiveness of brief CT added to maintenance AD versus maintenance AD alone versus guided tapering or discontinuation of AD with brief CT.2) examine whether the…
Aim of the study is to evaluate the effectiveness and cost-effectiveness of a positivity training based on attention bias modification as waitlist-intervention for adult outpatients with a major depressive disorder.
The primary objective of this study is to evaluate the long-term safety and tolerability of LY2216684 administered once daily (QD) in the adjunctive treatment with a selective serotonin reuptake inhibitor (SSRI) for up to approximately 1 year in…
We aim to (1) improve differential diagnosis of recurrent MDD and BD by investigating biomarkers at a neuropsychological and neurobiological level ; (2) investigate whether affective neuropsychological testing can be used as a diagnosios tool for…
To determine the influence of the serotonin transporter activity on the plasma free serotonin and dopamine amount and the stored amount (in trombocytes) in three different populations (healthy controls, carcinoid patients and patients on medication…
Phase I: To investigate whether it is feasible to organize an international multi-centre pragmatic trial on individualised homeopathic add-on treatment using a semi-standardised algorithm in women with premenstrual disorders and usual care only. We…
To compare cerebral activity patterns during emotional and cognitive processing among depressed patients with CKD and patients with regular depression.
1) To examine whether adolescents with depression, show abnormalities during specific attentional processes, compared to normal controls, 2) To determine whether abnormalities in attentional processes can be considered as prognostic markers of a…
The purpose of this study is to develop a webbased intervention for breast cancer patients to reduce the impact of psychological problems that arise after the completion of medical treatment at an early stage. The question is whether this…
Primary:1. to investigate the serotonergic HPA-axis activation (cortisol, ACTH, prolactin) in patients with a major depressive episode, using a newly developed oral 5-HTP-challenge administered before the first ECT treatment.2. to investigate the…
To study the effects and costs of a screening and treatment program for elderly with depressive symptoms in general practice.
1. We will explore the feasibility of homeopathic treatment with a semi standardised homeopathic prognostic treatment protocol for PMS in daily homeopathic practice. 2. We will evaluate the prognostic validity of using a semi standardised prognostic…
Primary:1. To establish the effect of MCP on the release of plasma AVP and subsequent ACTH and cortisol secretion in the absence of a 5HTP-challenge.2. To establish the effect of MCP on the release of plasma AVP and subsequent ACTH and cortisol…
The main objective of this study is to determine the validity and feasibility of the Beck Depression Inventory (BDI-II), the Hospital Anxiety and Depression Scale (HADS) and a short screening (3 questions), as a screening instrument for the…
The aim of the study is to:1. assess the prevalence of depression in patients with somatic illnesses admitted to the general hospital and to examine which self-report questionnaire is most suitable to screen for depression in this setting;2. to…