25 results
To investigate the impact of the multispecies probiotic product Ecologic*Barrier on neurocognitive measures of emotion and executive functioning.
The primary objectives are (1) to investigate the feasibility of online courses targeting nutrition and food-related behaviour and (2) to investigate whether the feasibility of the online courses is related to depressive symptoms. The secondary…
This study aims at the questions about anterograde amnesia. How often does it occur in patients being treated with bilateral ECT for a depressive disorder, how does anterograde amnesia develop during the treatment course and how does it subside…
Primary Objective: * To determine the effects of pharmacogenetic screening for CYP2D6 on the time to reach adequate serum drug levels according to the guidelines.Secondary Objective(s): * To determine the effects of pharmacogenetic screening for…
Aim of the study is to evaluate the effectiveness and cost-effectiveness of a positivity training based on attention bias modification as waitlist-intervention for adult outpatients with a major depressive disorder.
Phase I: To investigate whether it is feasible to organize an international multi-centre pragmatic trial on individualised homeopathic add-on treatment using a semi-standardised algorithm in women with premenstrual disorders and usual care only. We…
To compare cerebral activity patterns during emotional and cognitive processing among depressed patients with CKD and patients with regular depression.
1. We will explore the feasibility of homeopathic treatment with a semi standardised homeopathic prognostic treatment protocol for PMS in daily homeopathic practice. 2. We will evaluate the prognostic validity of using a semi standardised prognostic…
The aim of this project is to test the hypothesis that MDD patients with disturbances in anger/aggression regulation have more serotonin disturbances, as a trait marker for relapse, than MDD patients without disturbances in anger/aggression…
The main objective of this study is to investigate the effectiveness of the self-help program compared to a waiting-list control group in reducing depressive symptoms. Secondary objectives include the investigation of moderators and mediators of…
This study attempts to explore the relation between the functioning of the schema-related mPFC, REM sleep and affective memory bias, by simulating a depressive-like state in healthy subjects through negative mood induction and applying rTMS to…
To investigate the dynamic relationship between hemodynamic responses to different levels of acute SERT occupancy induced by different doses of the reuptake inhibitor (SSRI) citalopram with 5-HT phMRI, as compared to [123I]FP-CIT SPECT imaging.…
We investigate: (1) whether young women can be grouped according to distinct trajectories of depressive symptom change, measured with the Major Depression Inventory (MDI), over a period of 8 months following the breakup of a romantic relationship; (…
The aim of this study is to compare directly the activity of dopamine (DA) and norepinephrine (NE) in humans when they perform tasks that measure different aspect of cost-benefit evaluation (decision-making and learning) It is expected that blockade…
- To identify the relationship between fatigue and effort-based decision making in cancer survivors- To test whether effort-based decision making differs between cancer survivors and controls
Primary:o To compare effort- and/or reward-related neural activity between cancer survivors and healthy controlso To assess whether cancer-related fatigue is related to effort- and/or reward-related neural activitySecondary objectives:o To assess…
We aim to illustrate the relationship between early-life-adversity and emotional memory performance, and whether schema related neural activity during encoding and retrieval will contribute to the negative memory biases.
To assess utility and accuracy of an electroencephalography (EEG) -based brain network analysis platform as potential diagnostic tool for MDD, to correlate digital biomarkers and *gold standard* psychometric questionnaires such as MADRS in MDD and…
Objectives: - To identify and compare motivational behaviour in patients during different phases of cancer treatment. - To test its associations with self-reported fatigue/depression. - To determine to what extent treatment regimen, inflammation,…
Our primary objectives are to study: 1) differences in the brain*s sensitivity to the effects of light on emotional processing in people with PD and people with depressive symptoms compared with healthy controls 2) whether different spectrum of…