21 results
The aim of the project is to further develop and study the effectiveness of the Internet groupcourse Gripop Je Dip Online for young people (16-25 years) with depressive symptoms.Development objective:The eight-session groupcourse will be adapted…
My research proposal, therefore, will focus on the changeability (plasticity) of the ability to experience positive emotions in response to daily events (natural rewards), as a first step towards novel (preventive) interventions. The main question…
1) To examine whether adolescents with depression, show abnormalities during specific attentional processes, compared to normal controls, 2) To determine whether abnormalities in attentional processes can be considered as prognostic markers of a…
This study aims at gathering conclusive information about the effectiveness and efficiency of the secondDepression Breakthrough Collaborative and to make the results useful to other implementationprograms.This study aims to answer the following…
To study the effects and costs of a screening and treatment program for elderly with depressive symptoms in general practice.
The aim of this research is explaining the difference between worrying and rumination in adolescents. The following research question is investigated: On which dimensions can rumination and worrying be distinguished?For answering this question, a…
1. We will explore the feasibility of homeopathic treatment with a semi standardised homeopathic prognostic treatment protocol for PMS in daily homeopathic practice. 2. We will evaluate the prognostic validity of using a semi standardised prognostic…
To investigate the maintaining factor of mood-congruent memory bias of depression, the circumstances when they occur and the neural correlates of these.
Primary:1. To establish the effect of MCP on the release of plasma AVP and subsequent ACTH and cortisol secretion in the absence of a 5HTP-challenge.2. To establish the effect of MCP on the release of plasma AVP and subsequent ACTH and cortisol…
Zie onderzoeksprotocol
The aim of the study is to:1. assess the prevalence of depression in patients with somatic illnesses admitted to the general hospital and to examine which self-report questionnaire is most suitable to screen for depression in this setting;2. to…
Primary Objectives:- To investigate the effects of a single dose (plasma concentration) 5-HTP challenge test (5-HTP200mg/CBD100+50mg/granisetron2mg) on hypothalamic fMRS activation patterns in healthy male volunteers.Secondary Objectives:- To assess…
The objective is this study is fourfold: (1) The primary objective is the (construct-) validation of the SCM-typology. (2) A second objective is to explore the idiographic narrative assessment of depression.(3) A third objective is to explore the…
The study aims to gain insight in the costs, effects and process implications of the 4-5 session treatment as offered in the first line (GP practice) by the second line professionals(RIAGG) compared to direct referral to the RIAGG from a societal…
Primary objectives:1) Describe the PD effects on plasma ACTH and serum cortisol upon 100 µg hCRH injection with or without a preceding injection of 10 µg dDAVP 2 hours earlier and study the PK-PD relationship (*Block B*). In particular, the outcome…
Primary objective: the primary objective of the present study is to assess whether apathy can be linked to structural brain changes (both atrophy of grey matter, as well as changes in white matter), whether apathy in PD is related to certain…
the proposed study will examine the differences in flow-mediated vasodilatation of the brachial artery in depressed and non-depressed post-MI patients.
1. To investigate neuropsychological deficits during an ECT course in relationship to cortisol levels 2. To investigate the underlying neural correlates, i.e. functional connectivity, structural connectivity, and amygdala reactivity, that are…
The aim of this study is to investigate the role of the HPA-axis in MAS-disorders. By measuring cortisol in saliva the HPA-axis functioning can be determined (endophenotype), and by collecting buccal cells from which DNA will be isolated, single…
The study objective is the assessment of influence on glucose homeostasis as a consequence of starting switching, discontinuing or doses changes with antidepressants in a population of diabetic patients.