155 results
1. Is there a difference between the level of activities and participation among adolescents with chronic musculoskeletal pain as compared with the activity and participation level of adolescents not suffering from chronic pain?2. What is the impact…
The primary objective of this study is to determine the long-term clinical course in patients who consulted their general practitioner 6 years ago with a new episode of knee complaints. The secondary objectives of this study are to determine…
To investigate the effects of three different methods of finding a suitable recording site for CMAP and three different electrode sizes on CMAP amplitude and its reproducibility
The objective of the studie is to develop a reliable and discriminative measurment protocol to determine the upper extremity function in boys with DMD. This measurement protocol will be based on 3D movement analysis and surface EMG measurements.
To evaluate the clinical course in RA after cessation of TNF blockade and to determine biomarkers of successful cessation of TNF blockade.
Within this complete European consortium animal models as well as patient material are utilized, in order to uncover the pathogenic pathways in OPMD that are at the centre of the disease, eventually in order to design rational evidence based…
To determine the reproducibility and responsiveness of the Scapula Position Test and the WORC, WOSI and WOOS questionnaires in patients with shoulder symptoms.
In this study we want to investigate if relaxation time (RT) measured by handgrip myometry and muscle- elastography is a reliable outcome measurement for the quantification of myotonia in NDM patients. Mean RT values en standard deviations of NDM…
The aim of this study is to assess the effect of training on the measurement properties of a recently developed disease activity score based on patient reported outcomes and to investigate if such a measure could be implemented in current clinical…
In this study we want to monitor the neurological complications occurring during hip operations, consisting of hip arthroplasty ('head-neck' prothesis) for traumatic hip fractures. We want to establish that there is more understanding of…
1. To include the patients* point of view in the characterization and description of the mucopolysaccharidoses; and to compare between the different types of mucopolysaccharidoses.2. To assess *health damage* at the moment of diagnosis, in order to…
The aim of this study is to evaluate the influence of extreme fixed wrist flexion and ulnar deviation due to spasticity on bone shapes of the wrist bones. We want to compare CT scan-based three-dimensional reconstructions of the spastic wrist to the…
The objective of the study is to be able to determine the contribution of blood inorganic phosphate to the signal observed in skeletal muscle.
In this study we want to investigate if the muscle-relaxation time (muscle-RT), calculated from force profiles obtained with two different experimental methods (1) voluntary handgrip- and (2) peripheral nerve stimulation myometry, is a reliable and…
The aim of the study is to evaluate the validity and reproducibility of the ambulatory system, containing IFS*s and IMS*s, with respect to a reference system, to measure the frontal knee moment during gait in patients with osteoarthritis. As a…
This study aims to gain insight into the effect of inflammatory factors on bone metabolism. For this purpose we formulated the following research questions:1. Which circulating inflammatory factors play a central role in the pathogenesis of general…
This will be a pilot study that aims to gain insight into the effect of Gaucher disease on bone metabolism. For this purpose we formulated the following research questions:What is the effect of inflammatory factors in the serum of patients with…
1. Assessment of sensitivity of several outcome measures in muscle force and function in Duchenne muscular dystrophy2. Assessment of reproducability of different outcome measures3. Assessment of clinical relevance of measured change over time in…
Primary objective:To determine the hepcidin levels before, 2, 4, 8 and 24 hours after the administration of anti-IL-6R in patients with RA.Secondary objective:To determine the levels of Iron, transferrin , (calculation of transferrin saturation),…
The primary goal is investigating the number of women that have lymphedema five years after the treatment for breast cancer. In the describing part of this study, the focus will be on the correlation between lymphedema and 1) surgical treatment, 2)…