204 results
The aim of this study is to evaluate the long-term imaging and functional outcomes of overuse injuries of the wrist in (former) athletes.
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
The aim of the current project is to evaluate the long-term effects of a) a pragmatic lifestyle intervention aimed at weight loss and b) a 30-month placebo-controlled intervention with glucosamine sulphate on the development of knee osteoarthritis…
Primary aim: Stepwise feasibility study to investigate whether intravenously administered macrophage tracers [11C]DPA-713, [18F]DPA-714 and/or [18F]PEG-folate accumulate in inflamed joints of rheumatoid arthritis patients using PET(-CT).Secondary…
The main objective is to identify objective, neuromuscular and/or mechanic parameters through movement analysis, which are closely correlated to the subjective outcome of TKA. Secondary objective is to generate parameter specific hypotheses for our…
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
The aim of this exploratory study is to compare the hemodynamic response as determined by the HandScan between patients with OA and RA, and to study these hemodynamic responses in relation to disease specific underlying joint pathology (synovial…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.
Objective: We want to extend our understanding of the disease aetiology by performing a small pilot study that incorporates other immunologic sites involved in the disease (the skin and the microbiome) while additionally strengthening our disease…
Define the normal outcome and spread of the range of motion of the knee-rotationThe outcome of the manual rotationtest of the knee compared with a rotation-device. (reliability of the test)Define inter- and intra-tester reliability of the manual…
PRIMARY OBJECTIVETo identify the cellular mechanism behind early antidrug antibody (ADAb) production related to humoral responses within first 3 months of BP treatment.SECONDARY OBJECTIVES- To identify the affinity maturation process in ADAb…
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
Arthroscopic Optical Coherence Tomography in imaging of Trapeziometacarpal joint articular cartilage
In-vivo visualization of TMC articular cartilage using intra-articular fiber-optic OCT during TMC arthroscopy.
To estimate the prevalence and burden of disease of PsA among PsO patients in primary care,.To test the ability of the PEST(1), the PASE(2) and the EARP(3) to detect cases with PsA in primary care.To develop an easy applicable prediction rule for…
Primary objective:Pharmacokinetics/-dynamics of 124I-F8IL10 Secondary objective:Dosimetric parameters of arthritic joints and internal organs.
To evaluate the clinical impact of the CaFaSpA referral rule in young patients presenting at the general practioners with chronic low back pain, who are at risk for axSpA, compared to usual care.
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
In one FOA family we have detected a deleterious mutation in a compelling gene which co-segregates with the FOA phenotype in the family. This mutation is, therefore, is likely to be causal to the early onset OA. The objective of the study is:a) To…
In the present study we evaluate the change in quality of cartilage and bone as a result of KJD and of HTO. Based on the results of this pilot study, we will design a clinical study, with sufficient power, using the most promising sequences to…
To assess the prevalence, severity and impact of arthropathy in patients with moderate or severe VWD and a history of documented DDAVP or clotting factor concentrate treatment for joint bleeds. To compare arthropathy in these patients to age, FVIII…