358 results
The goal of this study is therefore to investigate whether the ingestion of mealworm protein can stimulate muscle protein muscle growth after a single endurance exercise session.
The first aim of this study is to use an in vitro approach using patient*s derived material to accurately and rapidly predict the optimal therapeutic approach that will predict a good clinical response in individual patients. The second aim of this…
Objective1) Validate the biomarker potential of CXCL10, TNFR2, and galectin-9 in disease activity monitoring of JDM and DM.2) Determine the role of IL-18, CCL2, CCL4, CCL19, CCL27, CXCL10, CXCL13, TNFR1, TNFR2, galectin-9 and other potential…
Primary* To assess and characterize the local effect of the FIRTECH patch on local microcirculation.Secondary* To evaluate the effect of the FIRTECH patch on tissue oxygenation and perfusion.* To evaluate the local effect of the FIRTECH patch on…
To determine the effect of a personalized lifestyle program on endurance, muscle strength, muscle function, core stability, quality of life, bone mineral density, body composition, energy expenditure, physical activity, muscle morphology,…
With the extended LAST STRONG Study, we aim to (1) collect 3-year and 5-year natural history data, (2) implement the natural history data collection into clinical care and international guidelines (reach trial readiness), and (3) do in-depth…
In this exploratory study we aim:1) To identify the confounding factors in qMRI analysis (e.g. age, gender, body composition)2) To determine the relation between qMRI parameters and muscle force and function taking into account the confounding…
To study the effectiveness of physiotherapy plus an eHealth psychological intervention targeted at psychosocial risk factors compared to usual physiotherapy care on disability, for patients at risk of developing persistent low back pain and neck…
This study has been transitioned to CTIS with ID 2024-515129-27-00 check the CTIS register for the current data. In our phase IIa trial we will determine the effect and safety of three MABs administrations in the m. biceps brachii in m.3243A>…
Primary Objective:1) To determine the efficacy of personalized progressive resistance training (PRT) on muscle strength of elbow flexors in children and adolescents with Spinal Muscular Atrophy and Congenital Myopathy compared to usual care…
To compare the effectiveness of a diet with beef as key protein source versus an isocaloric and isonitrogenous plant-based diet to stimulate integrated muscle protein synthesis rates over a 10 day period, in healthy older individuals, with and…
This study has been transitioned to CTIS with ID 2023-508284-77-00 check the CTIS register for the current data. The purpose of this study is to evaluate the safety and efficacy of ALXN1720 for the treatment of gMG in adults with autoantibodies…
The primary objective is - To clinically validate the inter-observer reliability of compressibility measurements with the CPM#1 device during rest in healthy volunteers.
Hoofddoel: We aim to assess the utility of ultrasound-defined contractile performance as a biomarker for monitoring disease progression and treatment effects in patients with FSHD.Stage I:Primary Objective:To establish the feasibility, optimal…
The goal of this study is to investigate the most optimal way of canola protein processing on blood plasma amino acid responses in young females.
Objective of the validation study is evaluating the optimal imaging modality, diffusion tensor magnetic resonance imaging (DT-MRI) or ultrasound, for measuring pennation angle and fascicle length, muscle thickness, muscle volume and cross sectional…
Aim of the study is to ascertain the order of magnitude to which ESWT may improve the performance of specific activities of daily living (ADL), measured by Goal Entertainment Scaling (GAS) in people with spinal cord injury and spasticity in the…
This study aims to investigate (1) the effectiveness of Nordic Hamstring Exercise for preventing hamstring re-injuries (2) the effectiveness of Nordic Hamstring Exercise for enhancing performance following Return to Play after hamstring injury.
The objective of the study is to investigate the feasibility of a combined resistance exercise training (RET) and protein supplementation (ONS) intervention and explore the effect on muscle mass and other parameters compared to standard of care in…
The primary objectives for this study are:To evaluate the preventive effect of GYM329 on disuse muscle atrophy in healthy male volunteers through changes in muscle strength following a single subcutaneous administration prior to unilateral thigh and…