358 results
Identification of the molecular and cellular muscular mechanisms associated with aging in rotator cuff muscles with radiological quantification and clinical data.
Do healthy adult males, age 4-70 years without cardio- or pulmonary disease reach a higher maximum oxygen uptake at cardiopulmonary exercisetest with the ramp-protocol in comparison to the standard bloc-protocol? P: healthy adult man, age 40 en 70…
This aim of this study is to evaluate the secondary outcome measures including three to four year re-injury data.
To define a dose-response relationship after intrinsically labeled milk protein ingestion on myofibrillar and mitochondrial muscle protein synthesis after a single bout of endurance exercise.
This study is not intended to improve your health, but is necessary for the further development of RO7034067 .The study will be performed in 3 parts, Parts 1, 2 and 3. This document only refers to Part 1/2/3 of the study . Part 1:A single dose will…
(1) To phenotype fibromyalgia patients in terms of endogenous modulation of pain, central sensitization/facilitation, the presence of a neuropathic pain component and small fiber neuropathy;(2) To assess the effect of a three-month treatment with…
From p12 of C1 protocol document:To assess how diurnal rates of muscle protein synthesis are altered during a short-term (3-day) implementation of resistance exercise training when compared to normal daily activity.
The primary aim of this study is to determine the effect of nandrolone decanoate (ND) injection and leucine supplementation on muscle mass loss during short-term immobilisation in healthy, young people. In addition, we aim to study the underlying…
To gain insight into the measurement properties of three questionnaires (part I) and the measurement properties of the upper limb functional capacity evaluation (part II). To gain insight in the effects of disorders of hand or wrist on health-…
The primary objectives of the study are to investigate the vitamin D status of Dutch children with motor disabilities attending a special needs school and to associate Vit D status to the level of physical functioning, other potential risk factors…
The primary objectives of this project are to assess the mtDNA mutation load in carriers of a mtDNA mutation and identify patients and/or mutations with with no/low mtDNA mutation load in mesoangioblasts. Secondary objectives aim at determining the…
Main Objective:To evaluate the long-term safety and tolerability of BYM338 in the treatment of sIBM and to further evaluate the effect of three BYM338dose regimens against placebo in increasing the distance traveled as measured by the 6 Minute…
Determine the reliability, validity and the sensitivity to change of the MYOTON Handheld Digital Palpation Device for measuring the severity of paratonia in patients with dementia and paratonia .Research questions are:(1) What is the validity of the…
This study aims to examine the feasibility and an indication of possible effects of an IROMEC robot based play therapy within rehabilitation and special education on the level of playfulness of children with severe physical disabilities.
To provide evidence for the efficacy of Branched Chain Keto Acids (BCKA) and Branched Chain Amino Acids (BCAA) when compared with milk proteins to stimulate postprandial muscle protein synthesis in vivo in healthy older humans.
This study examines the feasibility and an indication of possible effects of ZORA robot based intervention on play in rehabilitation and special education for children with severe physical disabilities.
In this phase I/II clinical study will assess the safety, effectiveness and homing of asCTMP, namely autologous mesoangioblasts, that will be injected 3x intra-arterially in right lower leg via catheter in 5 indivuals that carry the m.3243A>G…
This study aims to investigate the impact of a newly developed oral nutritional supplementation (ONS_01) primary on body weight and lean body mass and secondary on physical performance, muscle health and immune function in malnourished elderly…
- To assess the reproducibility of the LET.- To define the relation between the LET and clinical severity in HypoPP patients.
Objective: To evaluate the adherence of patient*s use of OS.