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Fighting fatigue! An intervention to reduce fatigue.

The objective of this study is to develop, test and evaluate a psychosocial intervention for dialysis patients aimed at better coping with, and reducing fatigue (primary outcome) and thus improving the quality of life (secondary outcome).

The efficacy of the walk-bike on quality of life and exercise capacity in patients with idiopathic pulmonary fibrosis: a pilot study.

Primary objective• To assess the effect of use of a walk-bike in IPF patients for 8 weeks on health-related quality of life, measured with the St. George Respiratory Questionnaire, at baseline, week 9 and week 18, in patients with IPF.Secondary…

Multiproblem Young Adults: a study on service use trajectories, neurobiological mechanisms and treatment effect in young adults with severe criminal, psychiatric and social problems.

With this integrative research project we will expand the knowledge on factors associated with problematic behavior in young adults. To elucidate why multiproblematic behavior in young adults exists in a persistent way we will explore the underlying…

e-COGRAT: The development, efficacy and implementation of *blended care* treatment in acquired brain injury-induced fatigue. First step: feasibility of e-COGRAT, a pilot study.

1) Is e-COGRAT usable within the ABI population?2) What are the patients* experiences with e-COGRAT?3) What are the therapists* experiences with e-COGRAT?4) What changes in the e-COGRAT are necessary?5) Does this pilot with e-COGRAT show a decline…

Wellbeingtherapy as a part of rehabilitation in psychotraumatreatment;A radomized controlled study of the positive effects from wellbeingtherapy during the phase of rehabilitation in psychotraumatreatment with adults

The objective of the study is to report about the effect on psychological wellbeing, post traumatic growth and relapse in PTSD symptoms by treating patients with WBT in comparisson with TAU during the rehabilitation in psychotraumatreatment.

A longitudinal randomized clinical trial of participants satisfaction of two mandibular implant-retained overdentures, with ball, bar or locator attachment, in patients with severe resorption of the mandible.

Primary Objective:Is there a difference in patient satisfaction of the treatment in patients with a edentulous mandibular atrophic ridge comparing treatment with 2 dental implants and one of the three attachment types: ball-attachments, bar-…

Clozapine in Daily Life: an Experience Sampling Pilot Study

To determine whether changes in affect of patients with schizophrenia occur after starting clozapine.

A longitudinal randomized clinical trial of participants satisfaction of three or four mandibular implant-retained overdentures, with bar attachment, in patients with severe resorption of the mandible.

Primary Objective:Is there a difference in patient satisfaction of the treatment in patients with a edentulous mandibular atrophic ridge comparing treatment with 3 dental implants and a multiple bar or treatment with 4 dental implants and a…

Treatment of deafferentiation pain using EMDR (Eye Movement Desensitization and Reprocessing)
A randomised-controlled trial including patient with nerve damage in the jaw area.

At time of publication

Accesible behavioural interventions in Youth Healthcare for sleeping problems in young children.

In the Netherlands, there is no accesible evidence-based method for the prevention and treatment of sleepingproblems in young children, that can be carried out by Youth Healthcare nurses. This study will, in addition to existing knowlede about the…

The effect evaluation of a multidiscipinary treatment in children with obesity.

The main parameter of the study is evaluation and effectiveness of the treatment program on Body Mass Index (BMI) (as defined by Cole et al) compared to a standard intervention (increased physical activity and nutrient advice). Also the…

Long term follow up in patients with intermittent claudication randomized for supervised exercise training or endovascular revascularization

To evaluate the long-term clinical effectiveness of patients with IC randomized for supervised exercise training orendovascular revascularization.

Safety of transurethral ultrasound directed injection of autologous myoblasts, fibroblasts and collagen in patients with urinary stress incontinence

Primary objective: To confirm the safety of the use of Urocell as a treatment for stress incontinence due to intrinsic sphinctre deficiency.Secondary ojectives: - To score the quelity of life with a standardized questionnaire and to score the level…

A comparison between intensive lumbar extensor resistance training and usual care provided by the GP for chronic a-specific low back pain patients: a RCT

To compare the effects of intensive resistance training of the lumbal extensors with usual care as provided and prescribed by the GP, for patients with chronic a-specific low back pain.

SOS-training Social skills and Street skills: Improving strength and reducing vulnerability for victimisation: a randomised controlled trial in addicted patients with psychiatric disorders

The goal of this study is obtaining knowledge about the effectiveness of a training that aims to decrease victimisation of dual diagnosis patients.The primairy research question is:- What is the effect of the SOS-training on the frequency of…

Empowering children with mitochondrial myopathy in dealing with fatigue.

The PowerMe study will analyse fatigue characteristics and severity in children and adolescents with mitochondrial myopathy and their families. Then a blended personalized cognitive behaviour therapy program for fatigue will be designed and tested,…

Graded Exposure in patients with Painful Diabetic Neuropathy

To investigate the effects of the cognitive behavioural intervention GEXP on physical activity and quality of life, hereby targeting specific fears in patients with PDN.Hypothesis: GEXP, as addition to usual care, increases the levels of physical…

Post-market Clinical Investigation of High-Volume Anesthesia (Local Tumescent Anesthesia) used with the miraDry Treatment for Axillary Hyperhidrosis

To collect safety and efficacy data from study participants that have been treated with the miraDry System using High Volume Anesthesia (HVA, also known as LTA or Local Tumescent Anesthesia) method as the local anesthesia delivery method.

Forensic Network Coaching: a randomised controlled trial investigating the effectiveness of a network coach in improving mental well-being and decreasing psychiatric problems and criminal recidivism.

In this study we will examine the effectiveness and time course of the addition of a forensic network coach to treatment as usual in improving mental well-being among a forensic psychiatric outpatient population. Patients will be randomly allocated…

Power 4 a Healthy Pregnancy-intervention: the impact on empowerment and diet quality of pregnant women

The objective of the study is to measure the impact of the P4HP intervention on the empowerment and diet quality of pregnant women.