7 results
(Primary) Determine whether measuring the expression level is a good functional test for confirming the genetic diagnosis in IRIDA by establishing the relation between the TMPRSS6 mRNA expression and the phenotype in IRIDA patients and their family…
In the current proposal, we propose an in vitro study to explore the interaction of malaria infection, the parasitized erythrocyte, and monocyte iron metabolism. We aim to study the role of hepcidin and to explore a) the pathways involved in malaria…
The main goal of the study is the identification of the mechanism of obesity related insulin resistance. We will study the relation between the different cell types in visceral and subcutaneous fat tissue and its influence on adipokine proflie.…
Which combinations of mutations in the HFE and HJV and other genes involved in iron metabolism are associated to iron overload?
The current study is designed to validate the secondary reference material identified in the previous study, and to produce a larger batch of this new calibrator for harmonization of worldwide hepcidin assays the next 5 years. For that reason, our…
To quantify the effect of ID on skeletal oxidative metabolism in patients with chronic HF with either preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction.
Assessing different modalities of ektacytometry in diagnosing thalassemia and/or iron disorders. Investigating the influence of hemoglobinopathies and iron disorders on red cell membrane deformability in comoparison with healthy controls.